Results 61 to 70 of about 43,427 (229)
Controlled Morphological Growth and Photonic Lasing in Cesium Lead Bromide Microcrystals
NanomaterialsMorphology plays a crucial role in defining the optical, electronic, and mechanical properties of halide perovskite microcrystals. Therefore, developing strategies that offer precise control over crystal morphology during the growth process is highly ...
Mamoon Ur Rashid +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Journal of Agricultural Machinery, 2014 Mechanical properties of grain are influenced by various factors including soil nutrients and grain moisture content at harvest time. In order to reduce mechanical losses, the design of different processing operations should be performed based on the ...
S Kordi +5 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Mechanical Damage Of Strawberry During Harvest And Postharvest Operations
Acta Technologica Agriculturae, 2015 Strawberry is a non-climacteric fruit with a limited harvesting period. Because of high susceptibility to mechanical damage, strawberry has a small postharvest life. In this research, an experiment was designed to study the mechanical damage phenomena in
Aliasgarian Saeed +3 more
doaj +1 more source
Optimization-Based Mechanical Perception for Peduncle Localization During Robotic Fruit Harvest [PDF]
, 2022 Miranda Cravetz +2 more
openalex +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
International Journal of Horticultural Science, 2013 In a two-year-study, disease incidence of Monilinia fructigena were quatified and the importance of certain fruit wounding agents was determined. The first infected fruits were observed at the beginning of August in 2011 and 2012. Disease development was
I. J. Holb
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source