The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Mechanical Properties and Parameter Optimization for the “Suitable Harvest” Stage of Vegetable Sweet Potato Shoot Tips in Mechanized Harvesting [PDF]
Haiyang Shen +6 more
openalex +1 more source
Harvest of table olives by mechanical harvesting equipment
In this work, we have evaluated the performance, of an electric comb equipped with five undulated fingers used for mechanized the harvesting of table olives. The first aim of the work was to test three different types of coating materials used for covering the fingers: Silicon (S), Vulcanized rubber (VR) and Natural rubber (NR).
openaire +3 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Evaluation of manual and mechanical sugar cane harvesting performance in Campos dos Goytacazes, RJ.
Ricardo Ferreira Garcia +1 more
openalex +2 more sources
Mechanical Harvesting of Peaches—Limited Potential [PDF]
D.M. Glenn +2 more
openalex +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Marker-trait association analysis for easy fruit destemming and mechanical harvestability traits in New Mexican chile pepper (Capsicum annuum L.) [PDF]
Ehtisham Shakeel Khokhar +5 more
openalex +1 more source
Fruit Removal and Recovery during Citrus Harvesting are Improved when Abscission Agent Applications are Used with Mechanical Harvesters [PDF]
Jacqueline K. Burns +2 more
openalex +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source

