Results 21 to 30 of about 5,335,934 (384)

Parametric investigation of an injection-jet self-powered Fontan circulation

open access: yesScientific Reports, 2022
Approximately $$1/2500$$ 1 / 2500 babies are born with only one functioning ventricle and the Fontan is the third and, ideally final staged palliative operation for these patients.
Ray Prather   +5 more
doaj   +1 more source

Metabolic Mechanisms in Heart Failure [PDF]

open access: yesCirculation, 2007
Although neurohumoral antagonism has successfully reduced heart failure morbidity and mortality, the residual disability and death rate remains unacceptably high. Though abnormalities of myocardial metabolism are associated with heart failure, recent data suggest that heart failure may itself promote metabolic changes such as insulin resistance, in ...
Ashrafian, Houman   +2 more
openaire   +5 more sources

Management of Mechanical Ventilation in Decompensated Heart Failure. [PDF]

open access: yes, 2016
Mechanical ventilation (MV) is a life-saving intervention for respiratory failure, including decompensated congestive heart failure. MV can reduce ventricular preload and afterload, decrease extra-vascular lung water, and decrease the work of breathing ...
Adams, Jason Y   +4 more
core   +4 more sources

The effect of decellularisation on the real time mechanical fatigue of porcine aortic heart valve roots.

open access: yesPLoS ONE, 2022
Decellularised heart valve roots offer a promising option for heart valve replacement in young patients, having the potential to remodel and repair. Replacement heart valves have to undergo billions of opening and closing cycles throughout the patient's ...
Amisha Desai   +4 more
doaj   +1 more source

Mechanisms driving the ageing heart [PDF]

open access: yesExperimental Gerontology, 2018
Cardiovascular disease (CVD) is the leading cause of death globally. One of the main risk factors for CVD is age, however the biological processes that occur in the heart during ageing are poorly understood. It is therefore important to understand the fundamental mechanisms driving heart ageing to enable the development of preventions and treatments ...
Rhys Anderson   +3 more
openaire   +6 more sources

Management of therapeutic anticoagulation in patients with intracerebral haemorrhage and mechanical heart valves

open access: yesEuropean Heart Journal, 2018
Aims Evidence is lacking regarding acute anticoagulation management in patients after intracerebral haemorrhage (ICH) with implanted mechanical heart valves (MHVs).
J. Kuramatsu   +60 more
semanticscholar   +1 more source

From mechanisms of heart failure to clinical heart success

open access: yesDisease Models & Mechanisms, 2023
Summary: This Editorial introduces DMM's new Special Issue on ‘Moving heart failure to heart success’. The Guest Editors reflect on how articles in the issue advance the cardiac research field.
Jeroen Bakkers   +3 more
openaire   +4 more sources

Mitochondrial Metabolism in Myocardial Remodeling and Mechanical Unloading: Implications for Ischemic Heart Disease

open access: yesFrontiers in Cardiovascular Medicine, 2021
Ischemic heart disease refers to myocardial degeneration, necrosis, and fibrosis caused by coronary artery disease. It can lead to severe left ventricular dysfunction (LVEF ≤ 35–40%) and is a major cause of heart failure (HF).
Min Jiang   +9 more
doaj   +1 more source

Anticoagulation for pregnant women with mechanical heart valves: a systematic review and meta-analysis

open access: yesEuropean Heart Journal, 2017
Aims To review maternal and foetal outcomes in women with mechanical heart valves (MHVs) treated with vitamin-K antagonists (VKAs), first-trimester heparin followed by VKAs (sequential treatment), low molecular weight heparin (LMWH) and unfractionated ...
R. D’Souza   +7 more
semanticscholar   +1 more source

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