Results 41 to 50 of about 5,335,934 (384)
Management of Intracranial Hemorrhage in the Setting of Mechanical Heart Valve Replacement Therapy
Applied Mechanics, 2023 The management of an intracranial hemorrhage in patients receiving anticoagulant therapy presents a significant challenge for medical professionals. Anticoagulant treatment is intended to prevent blood clotting, but it can worsen active brain bleeds ...
Sahar Khan, Faiz Syed, Milan Toma
doaj +1 more source
Mechanisms of CaMKII Activation in the Heart [PDF]
Frontiers in Pharmacology, 2014 Calcium/calmodulin (Ca(2+)/CaM) dependent protein kinase II (CaMKII) has emerged as a key nodal protein in the regulation of cardiac physiology and pathology. Due to the particularly elegant relationship between the structure and function of the kinase, CaMKII is able to translate a diverse set of signaling events into downstream physiological effects.
openaire +3 more sources
Circulation: Heart Failure, 2021 Supplemental Digital Content is available in the text. Background: Cardiogenic shock occurring in the setting of advanced heart failure (HF-CS) is increasingly common. However, recent studies have focused almost exclusively on acute myocardial infarction-
Jaime Hernandez‐Montfort +15 more
semanticscholar +1 more source
Computational modeling of acute myocardial infarction [PDF]
, 2016 This is an Accepted Manuscript of an article published by Taylor & Francis Group in Computer Methods in Biomechanics and Biomedical Engineering on October, 2016, available online at: http://www.tandfonline.com/10.1080/10255842.2015.1105965Myocardial ...
Kuhl, E., Sáez Viñas, Pablo
core +2 more sources
Modelling the cardiac response to a mechanical stimulation using a low-order model of the heart
Mathematical Biosciences and Engineering, 2021 Heart diseases are one of the leading causes of death worldwide, and a dysfunction of the cardiac electrical mechanisms is responsible for a significant portion of these deaths.
Nicholas Pearce, Eun-jin Kim
doaj +1 more source
Changes in left ventricular electromechanical relations during targeted hypothermia
Intensive Care Medicine Experimental, 2020 Background Targeted hypothermia, as used after cardiac arrest, increases electrical and mechanical systolic duration. Differences in duration of electrical and mechanical systole are correlated to ventricular arrhythmias.
Kristin Wisløff-Aase +5 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2020 Background Conventional fat quantification methods for rotator cuff muscles have various limitations, such as inconsistent reliabilities of the Goutallier grades and need for advanced techniques in quantitative MRI sequences.
Dokwan Lee +6 more
doaj +1 more source
The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction
Nature Communications, 2021 The beating heart adapts cardiac output to changes in mechanical load via incompletely understood mechanotransduction mechanisms. Here the authors show that the mechanosensitive Piezo1 channel serves as a mechanotransducer for directly converting ...
Fan Jiang +7 more
doaj +1 more source
Optimization of anticoagulant therapy in patients undergoing mechanical heart valve replacement
Фундаментальная и клиническая медицина, 2023 Acquired heart defects have a high prevalence among patients of different age groups and represent a significant social problem. To date, surgery remains the only effective option to treat acquired heart disease, and replacement of the dysfunctional ...
S. A. Tkachenko +7 more
doaj +1 more source
Mechanisms of Ischemic Heart Injury
Cells, 2022 Ischemic heart disease is a leading cause of morbidity and mortality worldwide [...]
openaire +3 more sources