Results 61 to 70 of about 5,335,934 (384)

Applying the UTAUT2 framework to patients’ attitudes toward healthcare task shifting with artificial intelligence

BMC Health Services Research
Background Increasing patient loads, healthcare inflation and ageing population have put pressure on the healthcare system. Artificial intelligence and machine learning innovations can aid in task shifting to help healthcare systems remain efficient and ...
Weiting Huang, Wen Chong Ong, Mark Kei Fong Wong, Eddie Yin Kwee Ng, Tracy Koh, Chanchal Chandramouli, Choon Ta Ng, Yoran Hummel, Feiqiong Huang, Carolyn Su Ping Lam, Jasper Tromp   +10 more
doaj   +1 more source

Multiresolution spatiotemporal mechanical model of the heart as a prior to constrain the solution for 4D models of the heart. [PDF]

, 2019
In several nuclear cardiac imaging applications (SPECT and PET), images are formed by reconstructing tomographic data using an iterative reconstruction algorithm with corrections for physical factors involved in the imaging detection process and with ...
Gullberg, Grant T, Liu, Jing, Ordovas, Karen, Segars, W Paul, Seo, Youngho, Shrestha, Uttam M, Veress, Alexander I   +6 more
core   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Reconstructing Complex Cardiac Excitation Waves From Incomplete Data Using Echo State Networks and Convolutional Autoencoders

Frontiers in Applied Mathematics and Statistics, 2021
The mechanical contraction of the pumping heart is driven by electrical excitation waves running across the heart muscle due to the excitable electrophysiology of heart cells. With cardiac arrhythmias these waves turn into stable or chaotic spiral waves (
Sebastian Herzog, Sebastian Herzog, Roland S. Zimmermann, Roland S. Zimmermann, Johannes Abele, Johannes Abele, Stefan Luther, Stefan Luther, Stefan Luther, Ulrich Parlitz, Ulrich Parlitz, Ulrich Parlitz   +11 more
doaj   +1 more source

Immune mechanisms in heart failure [PDF]

European Journal of Heart Failure, 2017
Elevated levels of circulating pro‐inflammatory biomarkers in patients with both ischaemic and non‐ischaemic heart failure (HF) correlate with disease severity and prognosis. Experimental studies have shown activation of immune response mechanisms in the heart to provoke cardiac adverse remodelling and cause left ventricular dysfunction.
Yingying Zhang, Yingying Zhang, Johann Bauersachs, Harald F. Langer   +3 more
openaire   +2 more sources

Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2015
Background Patients with mechanical heart valves (MHV) require warfarin to prevent thromboembolism. Although dabigatran was as effective as warfarin for stroke prevention in atrial fibrillation when compared with warfarin in patients with MHV, the study ...
I. Jaffer, A. Stafford, J. Fredenburgh, R. Whitlock, N. Chan, J. Weitz   +5 more
semanticscholar   +1 more source

A parallel interaction potential approach coupled with the immersed boundary method for fully resolved simulations of deformable interfaces and membranes [PDF]

, 2016
In this paper we show and discuss the use of a versatile interaction potential approach coupled with an immersed boundary method to simulate a variety of flows involving deformable bodies.
de Tullio, Marco D, Lohse, Detlef, Meschini, Valentina, Ostilla-Monico, Rodolfo, Querzoli, Giorgio, Spandan, Vamsi, Verzicco, Roberto   +6 more
core   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Experience with left ventricular assist device usage in the treatment of end-stage heart failure [PDF]

Кардіохірургія та інтервенційна кардіологія, 2017
Heart failure potentially developing in most of heart diseases is a progressive process associated with high morbidity and mortality. Almost 3/4 of patients die within five years after first hospitalization because of heart failure.
B.M. Todurov, G.I. Kovtun, I.M. Kuzmich, M.V. Goncharenko, A.M. Druzhyna, A.O. Shpachuk, O.M. Postupalsky, S.O. Sheludko, S.M. Sudakevych, O.V. Stanyshevskyi, A.Yu. Melnyk   +10 more
doaj  

Simultaneous assessment of mechanical and electrical function in Langendorff-perfused ex-vivo mouse hearts

Frontiers in Cardiovascular Medicine, 2023
BackgroundThe Langendorff-perfused ex-vivo isolated heart model has been extensively used to study cardiac function for many years. However, electrical and mechanical function are often studied separately—despite growing proof of a complex electro ...
Julien Louradour, Rahel Ottersberg, Rahel Ottersberg, Adrian Segiser, Adrian Segiser, Agnieszka Olejnik, Agnieszka Olejnik, Berenice Martínez-Salazar, Berenice Martínez-Salazar, Mark Siegrist, Mark Siegrist, Manuel Egle, Manuel Egle, Miriam Barbieri, Saranda Nimani, Nicolò Alerni, Yvonne Döring, Yvonne Döring, Yvonne Döring, Yvonne Döring, Katja E. Odening, Katja E. Odening, Sarah Longnus, Sarah Longnus   +23 more
doaj   +1 more source