Results 61 to 70 of about 5,542,649 (397)

Stable, covalent attachment of laminin to microposts improves the contractility of mouse neonatal cardiomyocytes. [PDF]

, 2014
The mechanical output of contracting cardiomyocytes, the muscle cells of the heart, relates to healthy and disease states of the heart. Culturing cardiomyocytes on arrays of elastomeric microposts can enable inexpensive and high-throughput studies of ...
Ashley, Euan A, Pruitt, Beth L, Ribeiro, Alexandre JS, Zaleta-Rivera, Kathia   +3 more
core   +2 more sources

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Outcomes related to hospital characteristics of heart transplant centers: A National Readmission Database analysis

JHLT Open
Background: This study showcases an analysis performed using the National Readmission Database (NRD) from 2016 to 2019 to analyze the impact of ownership, location, size, and teaching status of transplant centers on cardiac transplant outcomes.
Farshad Amirkhosravi, MD, MPH, Duc T. Nguyen, MD, PhD, Roberto Secchi Del Rio, MD, Edward A. Graviss, PhD, MPH, Nadia Fida, MD, Ashrith Guha, MD, MPH, Cindy Martin, MD, Eric Suarez, MD, Lin-Chiang Philip Chou, MD, Arvind Bhimaraj, MD, MPH   +9 more
doaj   +1 more source

Threshold-based quantification of fatty degeneration in the supraspinatus muscle on MRI as an alternative method to Goutallier classification and single-voxel MR spectroscopy

BMC Musculoskeletal Disorders, 2020
Background Conventional fat quantification methods for rotator cuff muscles have various limitations, such as inconsistent reliabilities of the Goutallier grades and need for advanced techniques in quantitative MRI sequences.
Dokwan Lee, Ki-Taek Hong, Wonhee Lee, Eun Kyung Khil, Guen Young Lee, Jung-Ah Choi, Yongnam Song   +6 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Applying the UTAUT2 framework to patients’ attitudes toward healthcare task shifting with artificial intelligence

BMC Health Services Research
Background Increasing patient loads, healthcare inflation and ageing population have put pressure on the healthcare system. Artificial intelligence and machine learning innovations can aid in task shifting to help healthcare systems remain efficient and ...
Weiting Huang, Wen Chong Ong, Mark Kei Fong Wong, Eddie Yin Kwee Ng, Tracy Koh, Chanchal Chandramouli, Choon Ta Ng, Yoran Hummel, Feiqiong Huang, Carolyn Su Ping Lam, Jasper Tromp   +10 more
doaj   +1 more source

Experience with left ventricular assist device usage in the treatment of end-stage heart failure [PDF]

Кардіохірургія та інтервенційна кардіологія, 2017
Heart failure potentially developing in most of heart diseases is a progressive process associated with high morbidity and mortality. Almost 3/4 of patients die within five years after first hospitalization because of heart failure.
B.M. Todurov, G.I. Kovtun, I.M. Kuzmich, M.V. Goncharenko, A.M. Druzhyna, A.O. Shpachuk, O.M. Postupalsky, S.O. Sheludko, S.M. Sudakevych, O.V. Stanyshevskyi, A.Yu. Melnyk   +10 more
doaj  

Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy [PDF]

, 2014
Chronic neurohormonal and mechanical stresses are central fea-tures of heart disease. Increasing evidence supports a role forthe transient receptor potential canonical channels TRPC3 andTRPC6 in this pathophysiology.
Andersen, Asger, Birnbaumer, Lutz, Jo, Su-Hyun, Kass, David A., Lee, Dong-ik, Lepore, John J., Liu, Ting, Marino, Joseph P., Rainer, Peter P., Schnackenberg, Christine G., Seo, Kinya, Shalkey Hahn, Virginia, Willette, Robert N., Xu, Xiaoping   +13 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source