Results 81 to 90 of about 5,335,934 (384)

An Optical Method for the In-Vivo Characterization of the Biomechanical Response of the Right Ventricle

Scientific Reports, 2018
The intraoperative in-vivo mechanical function of the left ventricle has been studied thoroughly using echocardiography in the past. However, due to technical and anatomical issues, the ultrasound technology cannot easily be focused on the right side of ...
A. Soltani, J. Lahti, K. Järvelä, S. Curtze, J. Laurikka, M. Hokka, V.-T. Kuokkala   +6 more
doaj   +1 more source

Dabigatran versus warfarin in patients with mechanical heart valves.

New England Journal of Medicine, 2013
BACKGROUND Dabigatran is an oral direct thrombin inhibitor that has been shown to be an effective alternative to warfarin in patients with atrial fibrillation. We evaluated the use of dabigatran in patients with mechanical heart valves. METHODS In this
J. Eikelboom, S. Connolly, M. Brueckmann, C. Granger, A. Kappetein, M. Mack, Jon Blatchford, Kevin Devenny, J. Friedman, K. Guiver, Ruth Harper, Y. Khder, M. Lobmeyer, H. Maas, J. Voigt, M. Simoons, F. Van de Werf   +16 more
semanticscholar   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Mechanisms of control of heart glycolysis [PDF]

European Journal of Biochemistry, 1998
This review focuses on the mechanisms of control of heart glycolysis under conditions of normal and reduced oxygen supply. The kinetic properties and the biochemical characteristics of control steps (glucose transporters, hexokinase, glycogen phosphorylase and phosphofructokinases) in the heart are reviewed in the light of recent findings and are ...
Louis Hue, Mark H. Rider, Christophe Depre   +2 more
openaire   +3 more sources

Current state-of-the-art of device therapy for advanced heart failure [PDF]

, 2014
Heart failure remains one of the most common causes of morbidity and mortality worldwide. The advent of mechanical circulatory support devices has allowed significant improvements in patient survival and quality of life for those with advanced or end ...
Lee, Lawrence S., Shekar, Prem S.
core   +2 more sources

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Late Pediatric Mechanical Thrombectomy for Embolic Stroke as Bridge Reinforcement From LVAD to Heart Transplantation

JACC: Case Reports, 2021
Although the left ventricular assist device is an important bridge to heart transplantation for patients with end-stage heart failure, it can also be a source of embolic stroke. We present a case of late intracranial mechanical thrombectomy performed for
Jean-François Hak, MD, Anne Moreau de Bellaing, MD, Grégoire Boulouis, MD, Charles-Joris Roux, MD, Basile Kerleroux, MD, Damien Bonnet, MD, PhD, Lucile Houyel, MD, Olivier Raisky, MD, PhD, Manoelle Kossorotoff, MD, Olivier Naggara, MD, PhD   +9 more
doaj  

Midterm outcomes of mechanical versus bioprosthetic valve replacement in middle-aged patients: An Indian scenario

Heart India, 2017
Objective: The goal of this study is to evaluate and compare the midterm outcomes of bioprosthetic heart valve replacement in terms of survival, valve-related events, quality of life, and economic aspects of treatment in population age 45 years and above
Dheeraj Sharma, Anula Sisodia, Sanjeev Devgarha, Rajendra Mohan Mathur   +3 more
doaj   +1 more source

Statistics of heart failure and mechanical circulatory support in 2020

Annals of Translational Medicine, 2020
Heart failure is increasing in prevalence, with approximately 26 million patients affected worldwide. This represents a significant cause of morbidity and mortality.
Robert E. Bowen, T. Graetz, D. Emmert, M. Avidan   +3 more
semanticscholar   +1 more source

At the Heart of Innovation: Jefferson’s Heart Transplant Program [PDF]

, 2017
Jefferson’s Heart Transplant Program reactivated this year with a new, system-wide approach to heart failure that makes innovative, evidence-based, comprehensive care more accessible to patients throughout the Delaware Valley.

core   +1 more source