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Mechanism-Based Pharmacodynamic Modeling [PDF]
, 2012 Pharmacodynamic modeling is based on a quantitative integration of pharmacokinetics, pharmacological systems, and (patho-) physiological processes for understanding the intensity and time-course of drug effects on the body. Application of such models to the analysis of meaningful experimental data allows for the quantification and prediction of drug ...
Melanie A, Felmlee +2 more
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Energies, 2020 The steeply inclined and extremely thick coal seams (SIETCS) under the condition of gob filling frequently suffer from the occurrence of rockbursts. Figuring out the mechanisms of rockbursts under this condition for taking targeted measures to mitigate ...
Shengquan He +6 more
doaj +1 more source
Bio-Chemo-Mechanical Models of Vascular Mechanics [PDF]
Annals of Biomedical Engineering, 2014 Models of vascular mechanics are necessary to predict the response of an artery under a variety of loads, for complex geometries, and in pathological adaptation. Classic constitutive models for arteries are phenomenological and the fitted parameters are not associated with physical components of the wall.
Jungsil, Kim, Jessica E, Wagenseil
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A pore-scale thermo–hydro-mechanical model for particulate systems
, 2020 A pore scale numerical method dedicated to the simulation of heat transfer and associated thermo–hydro-mechanical couplings in granular media is described.
R. Caulk +3 more
semanticscholar +1 more source
Modelling the thermo-mechanical volume change behaviour of compacted expansive clays [PDF]
, 2009 Compacted expansive clays are often considered as a possible buffer material in high-level deep radioactive waste disposals. After the installation of waste canisters, the engineered clay barriers are subjected to thermo-hydro-mechanical actions in the ...
Cui, Yu-Jun, Tang, Anh-Minh
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Modeling Mechanisms of Cell Secretion [PDF]
Acta Biotheoretica, 2010 Secretion is a fundamental cellular process involving the regulated release of intracellular products from cells. Physiological functions such as neurotransmission, or the release of hormones and digestive enzymes, are all governed by cell secretion.
TSANEVA ATANASOVA K +3 more
openaire +3 more sources
STUDY ON THE PERFORMANCE OF HIGH-MODULUSASPHALT CONCRETEPAVEMENT IN EXTREMECURVES OR STEEP SLOPES OF TRUNK HIGHWAY [PDF]
Civil Engineering Journal, 2020 With the purpose of the project, we determined the performance of high modulus asphalt concrete(HMAC) pavement in sharp curves or steep slopes of the trunk highway.
Honglei Zhang, Mingrui Yang, Youcheng Ma
doaj +1 more source
3D mechanical analysis of aeronautical plain bearings: Validation of a finite element model from measurement of displacement fields by digital volume correlation and optical scanning tomography [PDF]
, 2010 On Airbus aircraft, spherical plain bearings are used on many components; in particular to link engine to pylon or pylon to wing. Design of bearings is based on contact pressure distribution on spherical surfaces.
Doumalin, Pascal +4 more
core +2 more sources
A Fault Diagnosis Method of Contactor Based on Support Vector Classifier
Kongzhi Yu Xinxi Jishu, 2022 Contactors are widely used in power, distribution and power applications. Health of contactor is a key factor to the healthy operation of power system. In this paper, a dynamic model of armature movement in the process of contactor closing is established,
YANG Jiawei +4 more
doaj
Frontiers in Physiology, 2020 IntroductionRight ventricle (RV) failure is one of the most common symptoms among patients with repaired tetralogy of Fallot (TOF). The current surgery treatment approach including pulmonary valve replacement (PVR) showed mixed post-surgery outcomes.
Han Yu +11 more
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