Results 201 to 210 of about 518,370 (269)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Optimised Magnetic Field-Assisted Finishing Improves Surface and Mechanical Performance of CAD/CAM Titanium Abutments. [PDF]

Int Dent J
Lin L, Yu H, Yang G, Wang H, Chen Q, Cheng H, Wang Y, Pan Y.   +7 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Mechanical performance and life cycle assessment of a Persian gum-waste carpet fiber soil composite for landfill bottom liners. [PDF]

Sci Rep
Mohseninia M, Ghahremani M, Fattahi SM.
europepmc   +1 more source

Polymers in Sustainable Construction Composites: Rheology, Mechanical Performance, and Durability. [PDF]

Polymers (Basel)
Kaya Y, Kobya V, Ünverdi M, Mardani N, Mardani A.   +4 more
europepmc   +1 more source

Mechanical performance of sustainable concrete containing industrial waste admixtures of SF, FA, CCI, and crushed quartz at different water-binder ratios. [PDF]

Sci Rep
Ahmad SSE, Graf AAA, Bneni MK.
europepmc   +1 more source

Understanding the Role of PBAT Content and Raster Orientation on the Mechanical Performance of Material Extrusion 3D-Printed PLA/PBAT Objects. [PDF]

Polymers (Basel)
Jakab SK, Nagy AL, Lendvai L.
europepmc   +1 more source

Enhancing the Mechanical Performance of Laser Powder Bed Fusion Prepared 316L Stainless Steel by Deformation Post-Processing at Ambient Temperature. [PDF]

Materials (Basel)
Kocich R, Kunčická L.
europepmc   +1 more source