Results 201 to 210 of about 13,137,816 (371)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Temperature-Dependent Mechanical and Structural Properties of Uniaxially Strained Planar Graphene [PDF]

S. Erasmus, Ch. Skokos, G. Kalosakas
openalex   +1 more source

Effect of Partial Inclusion of Tiles and Brick Waste as Binders in SCM Elements on Fresh State and Early Age Mechanical Properties

, 2023
Melek Akgül, Serkan Etli
openalex   +2 more sources

Mechanical Properties of Solid Polymers: Third Edition

, 2012
I. M. Ward, J. Sweeney, Ward Sweeney
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Tailoring the Microstructure and Mechanical Properties of Phenolic Aerogels with Graphene Oxide. [PDF]

Gels
Hu C, Chen L, Lei Z, Li Y, Wang L, Yang Y, Zhao T, Li H.   +7 more
europepmc   +1 more source

Mechanical Property Improvement of Epoxy Composites by Electrospun SiO2 Nanofibers [PDF]

Davoud Khademi, Alireza Khademi, Masoud Pour   +2 more
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC. [PDF]

Glia
Bisseling Q, Passchier EMJ, Kirwan FM, Antonovaite N, Camerini S, Brignone MS, Freal A, Mansvelder HD, Ambrosini E, van der Knaap MS, Min R.   +10 more
europepmc   +1 more source

Synergistic Effect of Silanized Ramie Fiber and Montmorillonite Clay on the Mechanical, Thermal, and Dynamic‐Mechanical Properties of Polyester Composites [PDF]

Daniel Rossi Klein, Maria Eduarda Escher Maletz, Matheus Vinícius Gregory Zimmermann, Ademir J. Zattera, Daiane Romanzini   +4 more
openalex   +1 more source