Results 251 to 260 of about 1,339,441 (314)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mechanical Properties of Basalt-Polypropylene Hybrid Fiber-Reinforced Red Mud-Coal Metakaolin Geopolymer. [PDF]

Materials (Basel)
Zhao J, Yu G, Hu L, Dong Y, Liu H, Guo C, Wang Y.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Size-Dependent Mechanical Properties of Additively Manufactured Ti-6Al-4V Thin Walls. [PDF]

Materials (Basel)
Xie T, Ding C, Wang P, Huang M, Xu S, Wang Z, Tang H.   +6 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Effect of Cr on the Microstructure and Mechanical Properties of Cu-Ni-Si Alloys. [PDF]

Materials (Basel)
Wang H, Wang W, Chen Z.
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

The Mechanical Properties and Microstructural Evolution Mechanism of Carbonation-Cured Loess with Varying MgO Content. [PDF]

Materials (Basel)
Yang K, Liu L, Fan Z, Lu X, Jia C, Mu X, Liu B, Zheng J.   +7 more
europepmc   +1 more source

Impact of various storage media and time on mechanical properties of bovine root dentin. [PDF]

Sci Rep
Herzog J, Klümke ML, Stawarczyk B, Klimenta M, Kanzow P, Rödig T, Haupt F.   +6 more
europepmc   +1 more source