Results 111 to 120 of about 1,527,027 (341)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Effects of trace Ca addition on microstructure and mechanical properties of as-cast Mg-Sm-Gd-based alloy

open access: diamond, 2023
Kai Guan   +5 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Fourth order Superintegrable systems separating in Cartesian coordinates I. Exotic quantum potentials

open access: yes, 2017
A study is presented of two-dimensional superintegrable systems separating in Cartesian coordinates and allowing an integral of motion that is a fourth order polynomial in the momenta.
Marquette, Ian   +2 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Synergistic effect of rhenium and tungsten in nickel-based model single crystal superalloys

open access: yesJournal of Materials Research and Technology
Understanding the roles and synergistic effects of alloying elements is crucial for designing nickel-based single crystal superalloys. A systematic exploration has been conducted to identify the synergistic effect of rhenium (Re) and tungsten (W) on the ...
Wei Tan   +9 more
doaj   +1 more source

The Influence of Nitrogen Flow on the Stoichiometric Composition, Structure, Mechanical, and Microtribological Properties of TiN Coatings [PDF]

open access: gold, 2023
V. A. Lapitskaya   +7 more
openalex   +1 more source

Note on nonequilibrium stationary states and entropy

open access: yes, 2003
In transformations between nonequilibrium stationary states, entropy might be a not well defined concept. It might be analogous to the ``heat content'' in transformations in equilibrium which is not well defined either, if they are not isochoric ({\it i ...
D. Evans   +16 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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