Results 121 to 130 of about 1,446,577 (354)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Piezoelectric characteristics of PVA/DL-alanine polycrystals in d33 mode

iScience, 2023
Summary: In this study, polyvinyl alcohol (PVA)-mixed DL-alanine (PVA/DL-alanine) polycrystals are fabricated, and their piezoelectric characteristics in the d33 mode are investigated. The d33 piezoelectric coefficients of the PVA/DL-alanine polycrystals
Buil Jeon, Dongsoo Han, Giwan Yoon
doaj  

The Influence of Phosphorus and Sulphur on the Mechanical Properties of Steel [PDF]

, 1917
H. C. H. CARPENTER
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Physicochemical Properties of the Surface of Aqueous Solutions. IV. Classification of Mechanical Behavior of Several Aqueous Surfaces [PDF]

, 1953
Hideo Kimizuka
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Flow detectors having mechanical oscillators, and use thereof in flow characterization systems [PDF]

, 2003
An improved system (100), resonator flow detector (102) and method for characterizing a fluid sample that includes o injecting a fluid sample into a mobile phase of a flow characterization system (106), and detecting a property of the fluid sample > or ...
Kolosov, Oleg, Matsiev, L, Petro, Miroslav   +2 more
core  

Note on nonequilibrium stationary states and entropy

, 2003
In transformations between nonequilibrium stationary states, entropy might be a not well defined concept. It might be analogous to the ``heat content'' in transformations in equilibrium which is not well defined either, if they are not isochoric ({\it i ...
D. Evans, D. Ruelle, D. Ruelle, D. Ruelle, D.J. Evans, E. G. D. Cohen, F. Bonetto, G. Gallavotti, G. Gallavotti, G. Gallavotti, G. Gallavotti, G. Gallavotti, G. Gallavotti, G. Gentile, J. Lebowitz, L. Andrej, L.F. Cugliandolo   +16 more
core   +1 more source

Study on preparation and performance of alkali-activated low carbon recycled concrete: Corn cob biomass aggregate

Journal of Materials Research and Technology, 2023
The burning or accumulation of a large number of corn cobs in the countryside not only pollutes the environment but also takes up land, and it is of great significance to use agricultural solid waste to prepare green ecological construction materials for
Peihan Wang, Haibao Liu, Huijuan Guo, Yang Yu, Yuanxin Guo, Gongbing Yue, Qiuyi Li, Liang Wang   +7 more
doaj