Results 151 to 160 of about 1,527,027 (341)

Materials data handbook: Aluminum alloy 6061 [PDF]

open access: yes
A summary of the materials property information for aluminum alloy 6061 is presented. The scope of the information includes physical and mechanical properties of the alloy at cryogenic, ambient, and elevated temperatures.
Muraca, R. F., Whittick, J. S.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Manufacture of an ether-modified copolyester fiber with high physical performances and its applying feasibility for copper clad laminate (CCL) substrate of fifth generation long-term evolution (5 G LTE)

open access: yesNext Materials
Although L-Glass is a competent reinforced fiber for the copper clad laminate (CCL) substrate of fifth generation long-term evolution (5 G LTE), its high-cost and intricate manufacturing procedure consumes much energy and time, leading to high carbon ...
Yun-Ping Chang   +3 more
doaj   +1 more source

Optimization of an oxide dispersion strengthened Ni-Cr-Al alloy for gas turbine engine vanes [PDF]

open access: yes
The investigation was carried out to determine the optimum alloy within the Ni-16Cr-Al-Y2O3 system for use as a vane material in advanced aircraft gas turbine engines.
Grierson, R., Klarstrom, D. L.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Materials data handbook: Aluminum alloy 7075 [PDF]

open access: yes
A summary of the materials property information on aluminum alloy 7075 is presented. The scope of the information includes physical and mechanical properties of the alloy at cryogenic, ambient, and elevated temperatures.
Muraca, R. F., Whittick, J. S.
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

DEVELOPMENT IN RESEARCH ON THE MECHANICAL PROPERTY OF ADHESIVE JOINTS

open access: yesJixie qiangdu, 2016
The need to design lightweight structures and the increased use of lightweight materials in industrial field,has led to wide use of adhesive bonding. In order to improve the mechanical strength and reliability of adhesive joints,the research results of ...
WANG YuQi, HE XiaoCong, ZENG Kai
doaj  

Physical and mechanical properties of hydroponic lettuce for automatic harvesting

open access: gold, 2020
Wenqi Wang   +4 more
openalex   +1 more source

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