Results 61 to 70 of about 1,261,391 (292)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Effect of Thermo-Oxidative, Ultraviolet and Ozone Aging on Mechanical Property Degradation of Carbon Black-Filled Rubber Materials

open access: yesBuildings
Carbon black (CB)-filled rubber materials are extensively used in civil engineering seismic isolation. However, CB-filled rubber materials often experience mechanical property degradation because of exposure to environmental factors. To better understand
Bo Zhou   +4 more
doaj   +1 more source

Materials data handbooks on aluminum alloys [PDF]

open access: yes, 1973
Five handbooks have been prepared which describe up-to-date properties of the following wrought-aluminum alloys: 2014, 2219, 5456, 6061, and 7075. Each handbook is divided into twelve chapters.
Muraca, R. F., Whittick, J. S.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Constriction Channel Based Single-Cell Mechanical Property Characterization

open access: yesMicromachines, 2015
This mini-review presents recent progresses in the development of microfluidic constriction channels enabling high-throughput mechanical property characterization of single cells. We first summarized the applications of the constriction channel design in
Chengcheng Xue   +5 more
doaj   +1 more source

Rapid multiple property determination from bulk materials libraries prepared from chemically synthesized powders

open access: yesScientific Reports, 2022
A variety of high-performance materials are utilized in electrical, electronic, and mechanical systems. Such systems account for a significant fraction of the world’s electricity consumption.
Li Ping Tan   +3 more
doaj   +1 more source

Open string with a background B-field as the first order mechanics, noncommutativity and soldering formalism

open access: yes, 2007
To study noncommutativity properties of the open string with constant B-field we construct a mechanical action which reproduces classical dynamics of the string sector under consideration.
A. A. Deriglazov   +14 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Materials data handbook on Inconel Alloy 718 [PDF]

open access: yes, 1973
Handbook is divided into twelve chapters. Scope of information presented includes physical- and mechanical-property data at cryogenic, ambient, and elevated temperatures. This is supplemented with useful information in such areas as material procurement,
Muraca, R. F., Whittick, J. S.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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