Results 61 to 70 of about 291,303 (264)
Constriction Channel Based Single-Cell Mechanical Property Characterization
This mini-review presents recent progresses in the development of microfluidic constriction channels enabling high-throughput mechanical property characterization of single cells. We first summarized the applications of the constriction channel design in
Chengcheng Xue +5 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Mechanical properties of warped membranes
27 pages, 10 figures, submitted to Physical Review ...
Košmrlj, Andrej, Nelson, David
openaire +6 more sources
Carbon black (CB)-filled rubber materials are extensively used in civil engineering seismic isolation. However, CB-filled rubber materials often experience mechanical property degradation because of exposure to environmental factors. To better understand
Bo Zhou +4 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Sensors for mechanical properties
This paper presents devices to convert a wide range of physical and mechanical properties into a displacement which can subsequently generate an instrumentation signal. The application of physical principles as the basis of a practical transducer is but one fascinating aspect of instrumentation.
openaire +2 more sources
The morphologies and surface chemical properties of domestic T800 grade carbon fibers A and imported Toray T800H were characterized by means of scanning electronic microscopy(SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS).
LI Guo-li, PENG Gong-qiu, ZHONG Xiang-yu
doaj +1 more source

