Results 31 to 40 of about 2,467 (267)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The effect of mechanical reclamation on the wear of silica sand grains [PDF]
Metalurgija, 2008 The wear effect of silica sands is usually joined with many foundry processes during the fresh sand preparation. The significant effect of silica grains destruction by means of crushing, abrasion and attrition is caused by most of mechanical reclamation ...
Łucarz, M.
doaj
A Substrate-Reclamation Technology for GaN-Based Lighting-Emitting Diodes Wafer
Applied Sciences, 2017 This study reports on the use of a substrate-reclamation technology for a gallium nitride (GaN)-based lighting-emitting diode (LED) wafer. There are many ways to reclaim sapphire substrates of scrap LED wafers.
Shih-Yung Huang, Po-Jung Lin
doaj +1 more source
SYSTEM OF MACHINERY FOR COMPLEX MECHANIZATION FOR RECLAMATION WORK
Agricultural machinery and technologies, 2017 Meliorative fleet replacement and expansion of lands areas of melioration systems during radical improvement of not used, degraded layland are the two interconnected directions. They can be provided during introduction of science based modern System of technologies and machines for the complex mechanization of meliorative works. This System is the most
openaire +3 more sources
Proceedings of the Southwest State University, 2021 Purpose of research. Improving irrigation methods and techniques is the most important task of irrigated agriculture. In our country and abroad, a significant part of the area is watered by surface irrigation along furrows, strips and checks, which is most acceptable in the case of a sharp increase in the cost of energy carriers.
S. G. Novikov +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
IOP Conference Series: Earth and Environmental Science, 2023 Abstract The inaccessibility of forest areas dictates the need to optimize the ways of their reclamation in case of pollution. The northern regions are highly vulnerable. To determine the degree of pollution, a variant of mapping the site with the determination of the degree of pollution was considered. Water sampling in the contaminated
Elena Grafova, Vladimir Syunev
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source