Results 141 to 150 of about 448,246 (218)

Gamma Irradiation of Poly(lactide-co-glycolide) Scaffolds Reduces the Mechanical Stability and Function of Islet Grafts in Diabetic Nonhuman Primates. [PDF]

Biotechnol Bioeng
King JL, Spencer C, Youngblood R, Crumley K, Bealer E, Rios PD, Joshi I, Ghani S, Isa D, McGarrigle JJ, Cook D, Locke C, Abraham A, Clark A, Oberholzer J, Shea LD.   +15 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Effects of Tensile Specimen Geometry and Gripping System on the Mechanical Stability of Ausferrite in Austempered Ductile Irons. [PDF]

Materials (Basel)
Fu L, Schiralli M, Vedani M, Olofsson J, Górny M, Govahi P, Donnini R, Losurdo M, Angella G.   +8 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Cement Augmentation of the Blade in Proximal Femoral Nailing for Trochanteric Fractures in Elderly Patients: A Retrospective Comparison of Mechanical Stability and Complications. [PDF]

J Clin Med
Cibula Z, Grendar M, Sammoudi D, Cipkala M, Melisik M, Hrubina M.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Improved Mechanical Stability and Proton Conductivity of Reinforced Membranes for Proton Exchange Membrane Fuel Cells (PEMFCs). [PDF]

ACS Phys Chem Au
Kim JH, Noh MS, Shin EJ, Lee SY, Kim Y, Jung HJ, Lee HJ, Lee HI, Lim DH, Lee YS, Kim HS, Woo SH.   +11 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Mechanical stability of new‑generation meshes for M3 inguinal hernia repair: experimental pressure chamber testing of SWING‑Mesh and 3DMax MID Anatomical Mesh. [PDF]

Wideochir Inne Tech Maloinwazyjne
Zamkowski M, Tomaszewska A, Lubowiecka I, Karbowski K, Putko M, Śmietański M.   +5 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source