Mobile mechanical signal generator for macrophage polarization
The importance of mechanical signals in regulating the fate of macrophages is gaining increased attention recently. However, the recently used mechanical signals normally rely on the physical characteristics of matrix with non‐specificity and instability
Jiamiao Jiang +13 more
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Background: Steroid-induced Osteonecrosis of the Femoral Head (SIONFH) is a skeletal disease with a high incidence and a poor prognosis. Whole body vibration therapy (WBVT), a new type of physical training, is known to promote bone formation. However, it
Jia-Qing Tian +15 more
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In vivo cyclic loading as a potent stimulatory signal for bone formation inside tissue engineering scaffold [PDF]
In clinical situations, bone defects are often located at load bearing sites. Tissue engineering scaffolds are future bone substitutes and hence they will be subjected to mechanical stimulation. The goal of this study was to test if cyclic loading can be
A Roshan-Ghias +3 more
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CD73/5’-ecto-nucleotidase acts as a regulatory factor in osteo-/chondrogenic differentiation of mechanically stimulated mesenchymal stromal cells [PDF]
Bone regeneration is influenced by mesenchymal stromal cells (MSCs) and mechanical conditions. How healing outcome and mechanical stability are linked on the cellular level, however, remains elusive.
A Ode +6 more
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Tissue Engineering and Cell-Based Therapies for Fractures and Bone Defects
Bone fractures and segmental bone defects are a significant source of patient morbidity and place a staggering economic burden on the healthcare system.
Jose R. Perez +7 more
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Short-Term Effects of Arthroscopic Microfracturation of Knee Chondral Defects in Osteoarthritis
Purpose: The purpose of this study was to estimate the effect of platelet-rich plasma (PRP) augmentation in microfractures of chondral lesions in elderly individuals.
Przemysław Krakowski +4 more
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Naturally Engineered Maturation of Cardiomyocytes
Ischemic heart disease remains one of the most prominent causes of mortalities worldwide with heart transplantation being the gold-standard treatment option.
Gaetano J. Scuderi, Jonathan Butcher
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Mechanical stimulation of distraction regenerate. Mini-review of current concepts
Introduction One of the key limitations of distraction osteogenesis (DO) is the absence or delayed formation of a callus in the distraction gap, which can ultimately prolong the duration of treatment.
Alexander Cherkashin
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Recent Advances in Periodontal Regenerative Medicine: A Focus on the Role of Mechanical Stimulation
Periodontitis is a prevalent chronic inflammatory disease that leads to the progressive destruction of periodontal tissues and remains the primary cause of tooth loss worldwide.
Lidiia Grinchevskaia +7 more
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Enhancement of PC12 axonal extension via hybrid electromagnetic and mechanical stimulation
In this study, a hybrid electromagnetic and mechanical stimulation system that can apply an alternative current magnetic field (ACMF) and tensile strain fields on PC12 cells was developed to enhance nerve axonal extension. For the ACMF stimulation system,
Eiji NAKAMACHI +4 more
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