Results 61 to 70 of about 119,174 (264)

Wide Range Mechanical Customization of Mg-Gd Alloys With Low Degradation Rates by Extrusion

Frontiers in Materials, 2019
Currently, only a few magnesium alloys have been approved for implant applications. For biomedical purposes, the choice of the alloying elements is a critical parameter and rare earth elements have been proven to be mechanically suitable and biologically
Jochen Harmuth, Björn Wiese, Jan Bohlen, Thomas Ebel, Regine Willumeit-Römer   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Shear Properties and Failure Mechanism of Matched Discontinuities Between Two Different Rock Types Under Direct Shear

Applied Sciences
The shear mechanical properties of rock discontinuities with different joint wall compressive strengths are a practical basis for the stability analysis of layered rock mass.
Xiaobo Zhang, Shu Ouyang, Chenglong Fan, Le Yi, Da Liu   +4 more
doaj   +1 more source

Effects of calcined halloysite nano-clay on the mechanical properties and microstructure of low-clinker cement mortar

Case Studies in Construction Materials, 2019
This paper explores the effects of calcined halloysite nano-clay (CHNC) on the physico-mechanical properties and microstructure of high volume slag (HVS) cement mortar. The principal objective of this research is to constitute a low-clinker cement mortar
Sara Allalou, Rabia Kheribet, Abdelbaki Benmounah   +2 more
doaj   +1 more source

Effect of Surface Shape and Content of Steel Fiber on Mechanical Properties of Concrete

Advances in Civil Engineering, 2020
Steel fiber reinforced concrete (SFRC) has gained popularity in the last decades attributed to the improvement of brittleness and low tensile strength of concrete.
Lijuan Zhang, Jun Zhao, Cunyuan Fan, Zhi Wang   +3 more
doaj   +1 more source

Experimental Evaluation of the Mechanical Strengths and the Thermal Conductivity of GGBFS and Silica Fume Based Alkali-Activated Concrete. [PDF]

Materials (Basel), 2021
Parcesepe E, De Masi RF, Lima C, Mauro GM, Maddaloni G, Pecce MR.   +5 more
europepmc   +1 more source

The mechanical strength of film-coated tablets

Journal of Pharmacy and Pharmacology, 1979
AbstractThe mechanical strength of film-coated tablets has been assessed using the diametral compression test. The results show that the influence of the film is more complex than that suggested by Stern (1976). The film may increase the breaking load of the core itself by acting as a padding material during the test and also by filling in surface ...
J T, Fell, R C, Rowe, J M, Newton
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source