Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Data encryption using chaotic mechanical system vibration response signal [PDF]
, 2019 It is known that fractional derivatives are increasingly used due to the ability in describing memory effects and uncharacteristic behaviour which further combined with mechanical system to form chaos.
Poa, Jeffry Ming Xiong
core
Applied and Computational Mechanics, 2014 Experimental measurements focused on the investigation of a fibre behaviour are performed on an assembled weigh-fibre-pulley-drive mechanical system. The fibre is driven with one drive and it is led over a pulley. On its other end there is a prism-shaped
Polach P. +4 more
doaj
Design, simulation and analysis of micro electro-mechanical system microneedle for micropump in drug delivery systems. [PDF]
IET Nanobiotechnol, 2021 Karumuri SR +5 more
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Mechanical characterisation and modelling of resistance welding [PDF]
, 2010 Resistance welding is used very extensively in industry for a wide range of applications. Knowledge and measurement of the dynamic characteristics of resistance welding equipment is important in the design of the equipment and in optimization of ...
Van Rymenant, Patrick
core
Endoscopic optical coherence tomography angiography using inverse SNR-amplitude decorrelation features and electrothermal micro-electro-mechanical system raster scan. [PDF]
Quant Imaging Med Surg, 2022 Yao L, Li H, Liu K, Zhang Z, Li P.
europepmc +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Application of Initial Bias Estimation Method for Inertial Navigation System (INS)/Doppler Velocity Log (DVL) and INS/DVL/Gyrocompass Using Micro-Electro-Mechanical System Sensors. [PDF]
Sensors (Basel), 2022 Fukuda G, Kubo N.
europepmc +1 more source