Results 61 to 70 of about 20,243,593 (306)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Механика машин, механизмов и материалов, 2014 Main results of national R & D which correspond to world standards and were presented on the congress "Mechanics - 2013" are described.
A.A. Djuzhev, V.B. Algin
doaj
Energy-based Hamiltonian approach in H∞ controller design for n-degree of freedom mechanical systems
Systems Science & Control Engineering, 2019 This paper studies the energy-based approach for ${H_\infty } $ controller design of $n $-degree of freedom mechanical systems. In this approach, the Hamiltonian function, which is the sum of kinetic and potential energies of the system, is considered as
M. Karimi, T. Binazadeh
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Development of 18 t Eight-axle Passenger Electric Locomotive
机车电传动, 2016 How to put "lightweight" concept into the every detail of equipment layout, ventilation system, electrical system,mechanical system, braking system, and wind system for locomotive development was introduced.
YUAN Zhiqiang, WU Xueliang
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Reliability allocation for the mechanical system of autonomous underwater vehicles
, 2016 The reliability issue of the mechanical system of Autonomous Underwater Vehicles was analyzed. The system reliability models of the mechanical system of AUV were built under the conditions of random load and ultimate load, respectively.
Gu HT(谷海涛) +5 more
core
Mechanical Proof of the Second Law of Thermodynamics Based on Volume Entropy [PDF]
, 2007 In a previous work (M. Campisi. Stud. Hist. Phil. M. P. 36 (2005) 275-290) we have addressed the mechanical foundations of equilibrium thermodynamics on the basis of the Generalized Helmholtz Theorem.
Campisi, Michele
core +1 more source
Design and evaluation of an alternative wheelchair control system for dexterity disabilities
Healthcare Technology Letters, 2019 This work details the design and development of a novel 3D printed, modular alternative wheelchair control system for powered wheelchair users afflicted with dexterity inhibiting disorders, which mechanically interfaces directly with the installed ...
Samuel Oliver, Asiya Khan
doaj +1 more source