This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao+16 more
wiley +1 more source
Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality
Abstract Background Little is known about risk factors for mortality in older patients with COVID‐19 and neuropsychiatric conditions. Methods We conducted a multicentric retrospective observational study at Assistance Publique‐Hôpitaux de Paris. We selected inpatients aged 70 years or older, with COVID‐19 and preexisting neuropsychiatric comorbidities
Vi‐Huong Nguyen‐Michel+23 more
wiley +1 more source
Pressure-volume curves, static compliances and gas exchange in hyaline membrane disease during conventional mechanical and high-frequency ventilation [PDF]
J. Pfenninger, C Minder
openalex +1 more source
Mechanical Ventilation: Bilevel Ventilation (Respiratory Therapy) [PDF]
Laken, Debra Eddins
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xxxx. Abstract Nutrient metabolisms are vitally interrelated to cancer progression and immunotherapy. However, the mechanisms by which nutrient metabolisms interact to remodel immune surveillance within the tumor microenvironment remain largely unexplored.
Qi‐Long Wang+16 more
wiley +1 more source
COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
Abstract Introduction This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). Methods An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. Results Exacerbations of clinical symptoms
Syed Muhammad Ismail Shah+10 more
wiley +1 more source
Metabolic and respiratory effects of enteral nutrition in patients during mechanical ventilation [PDF]
Benno van den Berg, Henk J. Stam
openalex +1 more source
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee+5 more
wiley +1 more source
A Comparison of Pulmonary Artery Occlusion Pressure and Left Ventricular End-diastolic Pressure during Mechanical Ventilation with PEEP in Patients with Severe ARDS [PDF]
Jean–Louis Teboul+5 more
openalex +1 more source
Mechanical Ventilation: Pressure-Regulated Volume Control Ventilation (Respiratory Therapy) [PDF]
Moore, Christine J
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