Results 51 to 60 of about 2,917,850 (353)

Cost-utility Analysis of Home Mechanical Ventilation Compared to Hospital Settings in Patients with Amyotrophic Lateral Sclerosis

Current Directions in Biomedical Engineering, 2022
Amyotrophic lateral sclerosis is a progressive neuromuscular disease. Mechanical ventilation delays death and use at home can reduce costs and increase quality of life.
Gajdoš Ondřej, Rožánek Martin, Donin Gleb, Kamenský Vojtěch   +3 more
doaj   +1 more source

Variable mechanical ventilation [PDF]

Revista Brasileira de Terapia Intensiva, 2017
To review the literature on the use of variable mechanical ventilation and the main outcomes of this technique.Search, selection, and analysis of all original articles on variable ventilation, without restriction on the period of publication and language, available in the electronic databases LILACS, MEDLINE®, and PubMed, by searching the terms ...
Renata Bernardy Prestes, Gilberto Friedman, Paula Caitano Fontela, Luiz Alberto Forgiarini Jr.   +3 more
openaire   +2 more sources

Facioscapulohumeral muscular dystrophy and respiratory failure; what about the diaphragm?

Respiratory Medicine Case Reports, 2015
Introduction: We present a case of facioscapulohumeral muscular dystrophy (FSHD) with a diaphragm paralysis as the primary cause of ventilatory failure. FSHD is an autosomal dominant inherited disorder with a restricted pattern of weakness.
A. Hazenberg, N. van Alfen, N.B.M. Voet, H.A.M. Kerstjens, P.J. Wijkstra   +4 more
doaj   +1 more source

Association of Low Baseline Diaphragm Muscle Mass With Prolonged Mechanical Ventilation and Mortality Among Critically Ill Adults

JAMA Network Open, 2020
Key Points Question In mechanically ventilated patients, is diaphragm muscle mass at the outset of mechanical ventilation associated with clinical outcomes?
M. Sklar, M. Dres, E. Fan, G. Rubenfeld, D. Scales, M. Herridge, N. Rittayamai, M. Harhay, W. Reid, G. Tomlinson, D. Rozenberg, William L. McClelland, Stephen Riegler, Arthur S Slutsky, L. Brochard, N. Ferguson, E. Goligher   +16 more
semanticscholar   +1 more source

Mechanical ventilation

Nursing
: Mechanical ventilation is rarely a simple matter. Skill and knowledge are required to operate the ventilator modes, choose the optimal settings, and understand many monitored variables.
Bill Pruitt, Mary Catherine Hodges
semanticscholar   +1 more source

The mechanics of mechanical ventilation [PDF]

Revista Médica de Minas Gerais, 2014
The Ventilator has represented an advance in the respiratory support for patients on anesthesia and intensive care. The ventilatory support increases the chance of survival in patients with respiratory failure, and / or major surgical procedures. This paper consists of a summary of advances in the ventilatory support, in describing the physiological ...
Renan Murta Soares de Almeida, Aline Siqueira Melo, Cláudio Dornas de Oliveira   +2 more
openaire   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

How is mechanical ventilation employed in a pediatric intensive care unit in Brazil?

Clinics, 2009
OBJECTIVE: to investigate the relationship between mechanical ventilation and mortality and the practice of mechanical ventilation applied in children admitted to a high-complexity pediatric intensive care unit in the city of São Paulo, Brazil.
Dafne Cardoso Bourguignon da Silva, Audrey Rie Ogawa Shibata, Julio A Farias, Eduardo Juan Troster   +3 more
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source