Results 71 to 80 of about 3,417,663 (375)

Passive house ventilation strategies: demand control? [PDF]

, 2009
Since insulation levels in a passive house context are very high, energy losses trough ventilation are of relatively high importance in the total energy balance of a passive house concept.
Janssens, Arnold, Laverge, Jelle
core   +1 more source

Absolute electrical impedance tomography (aEIT) guided ventilation therapy in critical care patients: simulations and future trends [PDF]

, 2010
Thoracic electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring technique whose aim is to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting ...
Brown, B.H., Denai, M., Mahfouf, M., Mills, G.H., Mohamad-Samuri, S., Panoutsos, G.   +5 more
core   +2 more sources

Effect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Daily spontaneous breathing trials (SBTs) are the best approach to determine whether patients are ready for disconnection from mechanical ventilation, but mode and duration of SBT remain controversial.
C. Subirà, G. Hernández, A. Vázquez, R. Rodríguez-García, A. González-Castro, C. Garcia, O. Rubio, Lara Ventura, Alexandra López, M. C. de la Torre, E. Keough, V. Arauzo, C. Hermosa, C. Sánchez, A. Tizón, E. Tenza, C. Laborda, S. Cabañes, V. Lacueva, M. del Mar Fernández, A. Arnau, R. Fernandez   +21 more
semanticscholar   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Towards Safe Mechanical Ventilation Treatment Using Deep Offline Reinforcement Learning [PDF]

arXiv, 2022
Mechanical ventilation is a key form of life support for patients with pulmonary impairment. Healthcare workers are required to continuously adjust ventilator settings for each patient, a challenging and time consuming task. Hence, it would be beneficial to develop an automated decision support tool to optimize ventilation treatment.
arxiv  

Evaluation of parametrics for the development of vertical solar chimney ventilation in hot and humid climate [PDF]

, 2006
In terms of housing passive cooling design, tropical climatic regions present the most difficult problem to solve. A good dwelling design can keep the indoor environment favorable and comfortable during most of the year without the use of any mechanical ...
Ahmad, Mohd. Hamdan, Nugroho, Agung Murti, Then, Jit Hiung   +2 more
core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Guidance Value of Procalcitonin Detection in Selecting Switching Points for Sequential Therapy in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure

International Journal of COPD, 2022
Fang Ding,1 Wenjing Liu,2 Huiqing Wang,3 Weiwei Wang,1 Caixia Yang1 1Department of Geriatrics, Hengshui People’s Hospital, Hengshui City, Hebei Province, People’s Republic of China; 2Department of Respiratory Medicine, Hengshui People’s Hospital ...
Ding F, Liu W, Wang H, Wang W, Yang C
doaj  

A damaged-informed lung model for ventilator waveforms [PDF]

arXiv, 2020
The acute respiratory distress syndrome (ARDS) is characterized by the acute development of diffuse alveolar damage (DAD) resulting in increased vascular permeability and decreased alveolar gas exchange. Mechanical ventilation is a potentially lifesaving intervention to improve oxygen exchange but has the potential to cause ventilator-induced lung ...
arxiv