Results 81 to 90 of about 3,350,785 (417)

“Not Being Able to Talk Was Horrid”: A Descriptive, Correlational Study of Communication During Mechanical Ventilation [PDF]

open access: yes, 2015
Objectives: The purpose of this study was to describe the patient experience of communication during mechanical ventilation. Research methodology: This descriptive study is a secondary analysis of data collected to study the relationship between sedation
Bremmer, Karin Lindstrom   +2 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Guidance Value of Procalcitonin Detection in Selecting Switching Points for Sequential Therapy in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure

open access: yesInternational Journal of COPD, 2022
Fang Ding,1 Wenjing Liu,2 Huiqing Wang,3 Weiwei Wang,1 Caixia Yang1 1Department of Geriatrics, Hengshui People’s Hospital, Hengshui City, Hebei Province, People’s Republic of China; 2Department of Respiratory Medicine, Hengshui People’s Hospital ...
Ding F, Liu W, Wang H, Wang W, Yang C
doaj  

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

A damaged-informed lung model for ventilator waveforms [PDF]

open access: yesarXiv, 2020
The acute respiratory distress syndrome (ARDS) is characterized by the acute development of diffuse alveolar damage (DAD) resulting in increased vascular permeability and decreased alveolar gas exchange. Mechanical ventilation is a potentially lifesaving intervention to improve oxygen exchange but has the potential to cause ventilator-induced lung ...
arxiv  

Passive house ventilation strategies: demand control? [PDF]

open access: yes, 2009
Since insulation levels in a passive house context are very high, energy losses trough ventilation are of relatively high importance in the total energy balance of a passive house concept.
Janssens, Arnold, Laverge, Jelle
core   +1 more source

Review of mechanical ventilation for the non-critical care trained practitioner. Part 2

open access: yesJournal of Mechanical Ventilation, 2021
There have been a recent shortage of both critical care physicians and respiratory therapists with training in mechanical ventilation that is accentuated by the recent COVID-19 crisis.
Ehab G. Daoud, Rebecca Shimabukuro
doaj   +1 more source

Mechanics and Control of Ventilation

open access: yesSurgery (Oxford), 2003
The lungs are responsible for oxygenating the blood and removing carbon dioxide from the body. They are also responsible for a very substantial burden of disease in the UK and worldwide population, and for the cancellation or complication of many surgical procedures.
Talbot, N, Smith, T, Dorrington, K
openaire   +3 more sources

Evaluation of parametrics for the development of vertical solar chimney ventilation in hot and humid climate [PDF]

open access: yes, 2006
In terms of housing passive cooling design, tropical climatic regions present the most difficult problem to solve. A good dwelling design can keep the indoor environment favorable and comfortable during most of the year without the use of any mechanical ...
Ahmad, Mohd. Hamdan   +2 more
core  

HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium [PDF]

open access: yes, 2013
Background: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation.
Bonney, Megan   +9 more
core   +3 more sources

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