Results 91 to 100 of about 2,580,895 (365)

Conventional Mechanical Ventilation

Saudi Journal of Anaesthesia, 2010
The provision of mechanical ventilation for the support of infants and children with respiratory failure or insufficiency is one of the most common techniques that are performed in the Pediatric Intensive Care Unit (PICU). Despite its widespread application in the PICUs of the 21st century, before the 1930s, respiratory failure was uniformly fatal due ...
openaire   +4 more sources

Assessment of Nurses' Performance Regarding Management of Patients on Mechanical Ventilator

, 2016
Background: Mechanical Ventilation is widely used in the Intensive Care Units worldwide for various emergency indications. So, nurses must be knowledgeable about the function and limitations of ventilator modes, causes of respiratory distress and dys ...
Shaimaa Hesham
semanticscholar   +1 more source

Relationship between SARS-CoV-2 infection and the incidence of ventilator-associated lower respiratory tract infections: a European multicenter cohort study

Intensive Care Medicine, 2021
Purpose Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired infections is low.
A. Rouzé, I. Martín-Loeches, P. Póvoa, D. Makris, A. Artigas, M. Bouchereau, F. Lambiotte, Matthieu Metzelard, P. Cuchet, Claire Boulle Geronimi, Marie Labruyere, F. Tamion, M. Nyunga, C. Luyt, J. Labreuche, O. Pouly, Justine Bardin, A. Saade, P. Asfar, J. Baudel, A. Beurton, D. Garot, Iliana Ioannidou, Louis Kreitmann, J. Llitjos, E. Magira, B. Mégarbane, David Meguerditchian, E. Moglia, A. Mekontso-Dessap, J. Reignier, M. Turpin, Alexandre Pierre, G. Plantefeve, C. Vinsonneau, Pierre-Edouard Floch, N. Weiss, A. Ceccato, A. Torres, A. Duhamel, S. Nseir, Raphaël Sébastien Mercé Julien Chaouki Piehr Hanane Franço Favory Preau Jourdain Poissy Bouras Saint Leger Fo, R. Favory, S. Préau, M. Jourdain, J. Poissy, Chaouki Bouras, Piehr Saint Leger, Hanane Fodil, François Aptel, Thierry van der Linden, A. Thille, É. Azoulay, F. Pène, K. Razazi, F. Bagate, D. Contou, G. Voiriot, D. Thévenin, B. Guidet, L. le Guennec, A. Kouatchet, S. Ehrmann, G. Brunin, E. Morawiec, A. Boyer, L. Argaud, S. Voicu, A. Nieszkowska, Benjamin Kowalski, G. Gomà, E. Díaz, L. Morales, Vassiliki Tsolaki, George Gtavriilidis, S. Mentzelopoulos, D. Nora, Sean Boyd, L. Coelho, J. Maizel, D. du Cheyron, Mehdi Imouloudene, J. Quenot, A. Guilbert, C. Cillóniz   +84 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Patient-ventilator asynchronies during mechanical ventilation: current knowledge and research priorities

Intensive Care Medicine Experimental, 2019
Mechanical ventilation is common in critically ill patients. This life-saving treatment can cause complications and is also associated with long-term sequelae. Patient-ventilator asynchronies are frequent but underdiagnosed, and they have been associated
C. de Haro, A. Ochagavía, J. López-Aguilar, S. Fernández-Gonzalo, Guillem Navarra-Ventura, R. Magrans, J. Montanyà, L. Blanch   +7 more
semanticscholar   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Comparison between a clinical diagnosis method and the surveillance technique of the Center for Disease Control and Prevention for identification of mechanical ventilator-associated pneumonia

Revista Brasileira de Terapia Intensiva, 2015
Objective >To evaluate the agreement between a new epidemiological surveillance method of the Center for Disease Control and Prevention and the clinical pulmonary infection score for mechanical ventilator-associated pneumonia detection.
Renata Waltrick, D. S. Possamai, F. P. de Aguiar, Micheli Dadam, Valmir João de Souza, L. R. Ramos, Renata da Silva Laurett, Kênia Fujiwara, Milton Caldeira, Álvaro Koenig, G. Westphal   +10 more
semanticscholar   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte, Berta Estévez‐Arias, Leslie Matalonga, Delia Yubero, Anna Codina, Carlos Ortez, Julita Medina, Lidia DeSena DeCabo, Laura Carrera‐García, Jesica Expósito‐Escudero, Cristina Jou, Eduardo F. Tizzano, Andres Nascimento, Daniel Natera‐de Benito   +13 more
wiley   +1 more source

Is mechanical power the final word on ventilator-induced lung injury?-no.

Annals of Translational Medicine, 2018
Despite being a promising idea that combines several variables related to ventilator-induced lung injury (VILI), the concept of mechanical power (MP) carries a number of limitations, leaves several open questions, lacks proper modelling of positive end ...
R. Huhle, A. Serpa Neto, M. Schultz, M. Gama de Abreu   +3 more
semanticscholar   +1 more source