Results 151 to 160 of about 121,296 (347)

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo   +16 more
wiley   +1 more source

Partitioning Mechanical Ventilator Duration in COVID-19-related Acute Respiratory Distress Syndrome. [PDF]

open access: yesAm J Respir Crit Care Med, 2022
Gendreau S   +7 more
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

IMPLEMENTATION OF A DYNAMIC AND EXTENSIBLE MECHANICAL VENTILATOR MODEL FOR REAL-TIME PHYSIOLOGICAL SIMULATION. [PDF]

open access: yesAnnu Model Simul Conf ANNSIM, 2022
Webb JB   +6 more
europepmc   +1 more source

Mechanical Ventilation [PDF]

open access: yesAnnals of Emergency Medicine, 2018
openaire   +2 more sources

Patient-ventilator asynchronies during mechanical ventilation: current knowledge and research priorities [PDF]

open access: gold, 2019
Candelaria de Haro   +8 more
openalex   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

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