Results 311 to 320 of about 2,580,895 (365)
Animal Models and Experimental Medicine, EarlyView.This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin +9 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Blood pressure increases immediately when the 2K2C rats (made with 0.3, 0.25, and 0.2 mm U‐shaped clips) regain consciousness from anesthesia. 100% of the rats develop hypertension on the day of 2K2C surgery. Blood pressure continues to rise, resulting in severe hypertension and organ damage to the brain, heart, aorta, and kidneys at 1, 2, 4, and 6 ...
Jia‐Sheng Tian +4 more
wiley +1 more source
A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment
Animal Models and Experimental Medicine, EarlyView.A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng +4 more
wiley +1 more source
Diosgenin ameliorates silica‐induced tuberculosis in rats
Animal Models and Experimental Medicine, EarlyView.Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu +5 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.This study investigated changes in pulmonary artery hemodynamics using a Flowire catheter and evaluated the accuracy of Doppler echocardiography in dogs with acute pulmonary thromboembolism (PTE). Ten healthy beagles were anesthetized, and acute pulmonary hypertension (PH) was induced by injecting 300‐μm dextran microspheres.
Tomohiko Yoshida +3 more
wiley +1 more source
AI in Neurology: Everything, Everywhere, All at Once Part 1: Principles and Practice
Annals of Neurology, EarlyView.Artificial intelligence (AI) is rapidly transforming healthcare, yet it often remains opaque to clinicians, scientists, and patients alike. This review, part 1 of a 3‐part series, provides neurologists and neuroscientists with a foundational understanding of AI's key concepts, terminology, and applications.
Matthew Rizzo, Jeffrey D. Dawson
wiley +1 more source
Phosphatemia is an Independent Prognostic Factor in Amyotrophic Lateral Sclerosis
Annals of Neurology, EarlyView.Objective The objective of this study was to evaluate the prognostic value of several muscle damage biomarkers. Methods Data from Piemonte and Valle d'Aosta Amyotrophic Lateral Sclerosis (PARALS) were considered for this study. Survival was defined as the time from diagnosis to death, tracheostomy, or the censoring date.
Rosario Vasta +18 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Despite its clinical heterogeneity, amyotrophic lateral sclerosis is unified by early and prominent alterations in cortical excitability, increasingly recognized as contributors to disease progression. This study assessed whether the ratio between motor evoked potential (MEP) amplitude, reflecting upper motor neuron integrity, and compound ...
Federico Ranieri +41 more
wiley +1 more source
Advances in Chlorinated Polyethylene: Properties, Applications, and Future Directions
Journal of Applied Polymer Science, EarlyView.This work highlights recent advances in the synthesis of chlorinated polyethylene (CPE), its versatile industrial applications, and emerging innovations driving its future development in sustainable materials. ABSTRACT Elastomeric chlorinated polyethylene (CM or E‐CPE) integrates the thermoplastic's dynamic processing properties with the elastomer's ...
J. I. Mnyango +7 more
wiley +1 more source
The Anatomical Record, EarlyView.Bioimaging of the sense organs and brain of fishes and reptiles. Left panel: 3D reconstruction of the head and brain of the deep‐sea viperfish Chauliodus sloani following diceCT. Right panel: A 3D reconstruction of a 70‐day‐old embryo head of the bearded dragon Pogona vitticeps following diceCT, showing the position of the segmented brain within the ...
Shaun P. Collin +9 more
wiley +1 more source