Impact of the modification of a cleaning and disinfection method of mechanical ventilators of COVID-19 patients and ventilator-associated pneumonia: One year of experience. [PDF]
Cureño-Díaz MA +9 more
europepmc +1 more source
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu +17 more
wiley +1 more source
The Impact of High-Flow Nasal Cannula Use on Patient Mortality and the Availability of Mechanical Ventilators in COVID-19. [PDF]
Gershengorn HB +6 more
europepmc +1 more source
1725 CARDIORESPIRATORY EFFECTS OF CHANGES IN THE DURATION OF POSITIVE PRESSURE IN THE NEWBORN INFANT ON MECHANICAL VENTILATORS [PDF]
Bijan Siassi +3 more
openalex +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Fighting a pandemic with mechanical ventilators. [PDF]
Tiruvoipati R, Botha J.
europepmc +1 more source
Characterization of Natural Ventilation Systems in Residential Buildings in Portugal - The Importance of Standardization [PDF]
The technical recommendations regarding ventilation in various countries propose average rates of one hourly renewal in main rooms (bedrooms and living/dining rooms) and four renewals per hour in service rooms (kitchens and bathrooms).
Freitas, Vasco, Pinto, Manuel
core
Patient-ventilator asynchronies during mechanical ventilation: current knowledge and research priorities [PDF]
Candelaria de Haro +8 more
openalex +1 more source
DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim +11 more
wiley +1 more source

