Results 51 to 60 of about 14,521 (283)

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

A Transparent Semicrystalline Polymer Used in Thermally Responsive Smart Window Application

Advanced Functional Materials, EarlyView.
A thermally responsive smart window is fabricated based on a transparent semicrystalline polymer via copolymerizing stearyl acrylate and ethoxylated trimethylolpropane triacrylate. The high transparency is achieved by restricting the crystal domain to nanometer size via ultraviolet curing at a high temperature.
Jiacheng Fan, Thomas Wakuta, HyeonJi Hong, Ying Liu, Yu‐Ching Chen, Rongke Xu, Yuxuan Guo, Jianghan Wu, Isabelle Winardi, Ting‐Hsuan Wu, Zhixin Xie, Yuan Meng, Qibing Pei   +12 more
wiley   +1 more source

Mechanics and Control of Ventilation

Surgery (Oxford), 2003
The lungs are responsible for oxygenating the blood and removing carbon dioxide from the body. They are also responsible for a very substantial burden of disease in the UK and worldwide population, and for the cancellation or complication of many surgical procedures.
Talbot, N, Smith, T, Dorrington, K
openaire   +3 more sources

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

Advanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung, Yujin Ahn, Joo Hun Lee, Seungju Yang, Seung Cheol Lee, Hyunjoon Kong, Hyun Jung Chung   +6 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Can Open Source Hardware Mechanical Ventilator (OSH-MVs) initiatives help cope with the COVID-19 health crisis? Taxonomy and state of the art

HardwareX, 2020
The field of Open Source Hardware Mechanical Ventilators (OSH-MVs) has seen a steep rise of contributions during the 2020 COVID-19 pandemic. As predictions showed that the number of patients would exceed current supply of hospital-grade ventilators, a ...
Simone Mora, Fábio Duarte, Carlo Ratti
doaj   +1 more source

Advanced Flame Retardant Strategies and Fire Performance Assessment for Safer Photovoltaics in Buildings: A Two‐Part Review

Advanced Functional Materials, EarlyView.
The integration of photovoltaic (PV) systems into building structures introduces distinct fire risks with critical implications for occupant safety. This review examines the key fire hazards associated with PV implementation and explores mitigation strategies, including flame‐retardant additives.
Florian Ollagnon, Olaia Aurrekoetxea‐Arratibel, Emma Gottis, Heng‐Yu Li, Xabier Olano‐Azkune, Matthieu Despeisse, Antonin Faes, Christophe Ballif   +7 more
wiley   +1 more source

1-year survival rate of SARS-CoV-2 infected patients with acute respiratory distress syndrome based on ventilator types: a multi-center study

Scientific Reports, 2023
The aim of this study was to evaluate the association between types of ventilator and the one-year survival rate of patients with acute respiratory distress syndrome (ARDS) due to SARS‑CoV-2 infection. This multi-center, retrospective observational study
Ata Mahmoodpor, Kievan Gohari-Moghadam, Farshid Rahimi-Bashar, Masoum Khosh-Fetrat, Amir Vahedian-Azimi   +4 more
doaj   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Efficacy and safety testing of a COVID-19 era emergency ventilator in a healthy rabbit lung model

BMC Biomedical Engineering, 2022
Background The COVID-19 pandemic revealed a substantial and unmet need for low-cost, easily accessible mechanical ventilation strategies for use in medical resource-challenged areas. Internationally, several groups developed non-conventional COVID-19 era
Luke A. White, Benjamin S. Maxey, Giovanni F. Solitro, Hidehiro Takei, Steven A. Conrad, J. Steven Alexander   +5 more
doaj   +1 more source