Results 131 to 140 of about 2,248,361 (334)

A method for time-resolved measurements of the mechanics of phagocytic cups [PDF]

, 2013
Matthias Irmscher, Arthur M. de Jong, Holger Kress, M.W.J. Prins   +3 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The effect of composite materials interfacial discontinuities on the impact safety of future composite rail vehicles

Engineering Reports
In contrast to single‐phase materials the manufacturing process of composites creates multiscale interfaces among constituent materials and between laminar multilayers.
Xiangdong Xue, Mark Robinson, Wei Zhang
doaj   +1 more source

Robust optimization and uncertainty quantification in the nonlinear mechanics of an elevator brake system [PDF]

, 2019
Piotr Wolszczak, Paweł Lonkwic, Américo Cunha, Grzegorz Litak, Szymon Molski   +4 more
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Numerical Investigation of Nucleotides’ Interaction Considering Changes Caused by Liquid Influences

Mathematics
This work is devoted to the interaction of nucleotides. The goal of this study is to learn or try to learn how the interaction between nucleotides with exposure to a liquid takes place.
Raimondas Jasevičius
doaj   +1 more source

Mechanisms, mechanisms, mechanisms: it really does all boil down to mechanisms [PDF]

Pain, 2016
openaire   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Variational ansatz for -symmetric quantum mechanics [PDF]

, 1999
Carl M. Bender, Fred Cooper, Peter N. Meisinger, Van M. Savage, Carl M. Bender, Fred Cooper, Peter N. Meisinger, Van M. Savage   +7 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source