Results 131 to 140 of about 516,257 (296)
Characterization of ribosome heterogeneity during endothelial to hematopoietic transition
FEBS Open Bio, EarlyView.The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian +4 more
wiley +1 more source
THEORIA. An International Journal for Theory, History and Foundations of Science, 2017 An argument recently proposed by Chirimuuta (2014) seems to motivate the rejection of the claims that every neurocognitive phenomenon can have a mechanistic explanation and that every neurocognitive explanation is mechanistic. In this paper, I focus on efficient coding models involving the so-called “canonical neural computations” and argue that ...
openaire +4 more sources
Errata : On the Statistical Mechanics of Liquids, and the Gas of Hard Elastic Spheres [PDF]
, 1944 O. K. Rice
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FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli +4 more
wiley +1 more source
Osmotic pressure‐induced calcium response states
FEBS Open Bio, EarlyView.Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao +2 more
wiley +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
FEBS Open Bio, EarlyView.Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
Mechanisms, mechanisms, mechanisms: it really does all boil down to mechanisms [PDF]
Pain, 2016 openaire +2 more sources