Results 141 to 150 of about 772,836 (322)

Editorial: Frontiers in Silk Science and Technology

open access: yesFrontiers in Materials, 2021
Nicola Maria Pugno   +4 more
doaj   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Mechanics of Schrodinger mechanics

open access: yes, 2004
Small perturbations of ideal turbulence obey the Schrodinger equation. Microscopically, the perturbation of turbulence corresponds to formation of small amplitude helices on straight vortex filaments. A helix behaves in the vorticity field of the fluid as a spin particle in the Stern-Gerlach experiment.
openaire   +2 more sources

Pluralistic Mechanism

open access: yesTHEORIA. An International Journal for Theory, History and Foundations of Science, 2017
An argument recently proposed by Chirimuuta (2014) seems to motivate the rejection of the claims that every neurocognitive phenomenon can have a mechanistic explanation and that every neurocognitive explanation is mechanistic. In this paper, I focus on efficient coding models involving the so-called “canonical neural computations” and argue that ...
openaire   +4 more sources

The effect of composite materials interfacial discontinuities on the impact safety of future composite rail vehicles

open access: yesEngineering Reports
In contrast to single‐phase materials the manufacturing process of composites creates multiscale interfaces among constituent materials and between laminar multilayers.
Xiangdong Xue, Mark Robinson, Wei Zhang
doaj   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

open access: yesFEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo   +2 more
wiley   +1 more source

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