Results 161 to 170 of about 772,836 (322)
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
SoK: Privacy Personalised -- Mapping Personal Attributes \& Preferences of Privacy Mechanisms for Shoulder Surfing [PDF]
Shoulder surfing is a byproduct of smartphone use that enables bystanders to access personal information (such as text and photos) by making screen observations without consent. To mitigate this, several protection mechanisms have been proposed to protect user privacy. However, the mechanisms that users prefer remain unexplored.
arxiv
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui+5 more
wiley +1 more source
A flexible needle has emerged as a crucial clinical technique in contemporary medical practices, particularly for minimally invasive interventions.
Hafiz Muhammad Muzzammil +4 more
doaj +1 more source