Results 81 to 90 of about 92,471 (256)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Influence of electropulsing on fatigue crack growth retardation in hot-work die steel

Mechanical Engineering Journal
Thermal fatigue-induced crack propagation is a major damage mode in molds, and effective countermeasures are required to reduce manufacturing costs. Although crack healing using high-density pulsed electric current has been studied, its effectiveness in ...
Sae TAKASHIRO, Yutaro SUGENO, Atsushi HOSOI, Hiroyuki KAWADA   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

19th Youth Symposium on Experimental Solid Mechanics

Acta Polytechnica CTU Proceedings
The 19th Youth Symposium on Experimental Solid Mechanics was held in Rome, in June 5 - 7, 2024. The 19th symposium continues both the long tradition of this conference series and introduces novel elements.
Editorial Foreword
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Analytical solutions for lined noncircular tunnels in deep ground considering hydromechanical coupling

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
This study provides a general analytical approach to predict the stresses and displacements of deep noncircular tunnels excavated in saturated elastic ground, considering the hydro-mechanical coupling, the interaction between rock and liner, and ...
E. T. Wang, H. N. Wang, F. Song, X. C. Jia   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Exfoliation of graphite via three-roll milling and production of films with high electrical conductivity and electromagnetic interference shielding

Journal of Materials Science: Materials in Engineering
The objective of this study was to develop ecofriendly graphene nanoplatelet (GNP)/polymer films with high electrical conductivity and excellent electromagnetic interference (EMI) shielding performance. We have shown that three-roll milling could produce
Emi Orihara, Ryota Takei, Kyohei Sugata, Yoshihiko Arao   +3 more
doaj   +1 more source