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Structure and Mechanism of Metallocarboxypeptidases

Critical Reviews in Biochemistry and Molecular Biology, 2008
Metallocarboxpeptidases cleave C-terminal residues from peptide substrates and participate in a wide range of physiological processes, but they also contribute to human pathology. On the basis of structural information, we can distinguish between two groups of such metallopeptidases: cowrins and funnelins.
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Helicase structure and mechanism

Current Opinion in Structural Biology, 2002
Structural information on helicase proteins has expanded recently beyond the DNA helicases Rep and PcrA, and the hepatitis C virus RNA helicase to include UvrB, members of the DEA(D/H)-box RNA helicase family, examples of DnaB-related helicases and RuvB.
Jonathan M, Caruthers, David B, McKay
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THE STRUCTURES OF HAMILTONIAN MECHANICS

Russian Mathematical Surveys, 1977
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Vinogradov, A. M., Kupershmidt, B. A.
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Bone as a mechanical structure

Journal of Biomechanics, 1982
Silence, in scientific literature, about a subject, means either that the subject is uninteresting, or that nothing, or everything, is known about it. Sometimes, however, it means that people think they know about it, but never get round to articulating their thoughts.
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Structural mechanisms of costimulation

Nature Immunology, 2002
Recent studies have highlighted the structural requirements for T cell costimulation and have revealed unusual modes of dimerization for the cytolytic T lymphocyte-associated antigen 4 (CTLA-4) costimulatory receptor and its B7 ligands. These distinctive quaternary structures potentially endow both receptor and ligand with bivalent binding properties ...
Jean-Claude D, Schwartz   +3 more
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NO synthase: Structures and mechanisms

Nitric Oxide, 2010
Production of NO from arginine and molecular oxygen is a complex chemical reaction unique to biology. Our understanding of the chemical and regulation mechanisms of the NO synthases has developed over the past two decades, uncovering some extraordinary features. This article reviews recent progress and highlights current issues and controversies.
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Composite Material Mechanics: Structural Mechanics

AIAA Journal, 1974
Introduction T purpose of this Survey is to review and bring together in an orderly fashion some of the principal contributions to the field of structural mechanics of structures containing composite materials. The topics of micromechanics and fracture, while quite important, are not considered in this Survey.
Bert, Charles W., Francis, Philip H.
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Structure and mechanism of kynureninase

Archives of Biochemistry and Biophysics, 2014
The kynurenine pathway is the major pathway of l-tryptophan catabolism in eukaryotes and some bacteria. In this pathway, kynureninase catalyzes the hydrolysis of l-kynurenine (in bacteria) or 3-hydroxy-l-kynurenine (in eukaryotes) to give anthranilic acid or 3-hydroxyanthranilic acid, respectively, and l-alanine.
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Transporter structure and mechanism

Trends in Neurosciences, 2004
During the past several decades, lac permease has assumed almost tutelary proportions as a model for cotransporters. This archetypical membrane protein now exerts its influence by the most dramatic means possible: its structure is solved. This article describes the configuration and implied transport mechanism of the bacterial lactose transporter and ...
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The causal structure of mechanisms

Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 2012
Recently, a number of philosophers of science have claimed that much explanation in the sciences, especially in the biomedical and social sciences, is mechanistic explanation. I argue the account of mechanistic explanation provided in this tradition has not been entirely satisfactory, as it has neglected to describe in complete detail the crucial ...
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