Results 101 to 110 of about 11,573,862 (305)
Analyses of Sampling Disturbance of the Lunar Surface in Direct Push Sampling Method
IEEE Access, 2018 The study of direct push sampling characteristics forms the theoretical basis for deep sampling tool design. In this paper, a ground test of the direct push sampling was carried out to analyze three influencing factors: tube diameter; friction ...
Dewei Tang +4 more
doaj +1 more source
, 2015 The Higgs mechanism at the graviton level formulated as a Vainshtein mechanism in time domains implies that the extra-degrees of freedom become relevant depending on the direction of time (frame of reference) with respect to the preferred time direction (
Arraut, Ivan
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
A Low-Energy Consumption Planning Method for Multi-Locomotion Wheel-Legged Mobile Robots
MachinesMobile robots can replace humans to fulfill tasks in dangerous environments, which has been a research focus in recent years. This paper proposes a wheel-legged mobile robot with multi-locomotion and a low-energy consumption planning method.
Jinfu Li +6 more
doaj +1 more source
Bidirectional drive and brake mechanism [PDF]
, 1991 A space transport vehicle is disclosed as including a body which is arranged to be movably mounted on an elongated guide member disposed in outer space and driven therealong.
Swan, Scott A.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
IL‐7R gene polymorphisms among patients with rheumatoid arthritis: A case–control study
Molecular Genetics & Genomic Medicine, 2019 Background Rheumatoid arthritis (RA) is the most common inflammatory disease which refers to bony erosions and joint destruction largely caused by genetic factors.
Mei Bai +5 more
doaj +1 more source
Study on propagation characteristics of laser in turbulent Rayleigh–Bénard thermal convection
The Journal of Engineering, 2019 The turbulent Rayleigh–Bénard (R–B) convection system contains the plume and the large-scale circulation structure, which causes the statistical inhomogeneity of the flow field.
Zhichao Zhou +7 more
doaj +1 more source