Results 331 to 340 of about 10,501,738 (419)

Leaky ribosomal scanning enables tunable translation of bicistronic ORFs in green algae. [PDF]

Proc Natl Acad Sci U S A
Dueñas MA, Craig RJ, Gallaher SD, Moseley JL, Merchant SS.   +4 more
europepmc   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

Unravelling Convergent Signaling Mechanisms Underlying the Aging-Disease Nexus Using Computational Language Analysis. [PDF]

Curr Issues Mol Biol
Junyent M, Noori H, De Schepper R, Frajdenberg S, Elsaigh RKAH, McDonald PH, Duckett D, Maudsley S.   +7 more
europepmc   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Editorial: Multi-omics technology: revealing the pathogenesis of diseases and the mechanism of drug efficacy of major diseases such as nutritional metabolism disorders and mental disorders. [PDF]

Front Pharmacol
Hao W, Liu T, Du X, Tao G.
europepmc   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

Corrigendum: Advances in application of hypoxia-preconditioned mesenchymal stem cell-derived exosomes. [PDF]

Front Cell Dev Biol
Zhuo H, Chen Y, Zhao G.
europepmc   +1 more source

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

FEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang, Jiang Tan, Xueting He, Yuqin Chen, Guoping Qiu, Mei Yang   +5 more
wiley   +1 more source

Editorial: Targeting cellular signalling pathways for disease therapy: the potential of cellular reprogramming and protein kinase inhibitors. [PDF]

Front Pharmacol
Marensi V, Oliveira PF, Zamoner A.
europepmc   +1 more source

Collagen Fibrillogenesis: A Mechanism of Structural Biology

Journal of Investigative Dermatology, 1986
openaire   +3 more sources