Results 211 to 220 of about 2,036,755 (365)

Design and competitive edge: A model for design management excellence in European SME's

open access: yes, 2002
This article suggests to use the conceptual model of Michael Porter Value Chain in order to integrate all the variables that explain the mechanism of value creation through design.
Borja de Mozota, B
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Deep mechanism design: Learning social and economic policies for human benefit. [PDF]

open access: yesProc Natl Acad Sci U S A
Tacchetti A   +8 more
europepmc   +1 more source

Parameter design and optimization for mobile mechanism of a transformable wheel-track robot

open access: yes, 2009
According to the terrain features of the irregular environment, we propose a novel mobile mechanism of the transformable wheel-track robot (TWTR). The TWTR can adapt autonomously to the irregular environment by transforming the track configuration or by ...
Ma SG(马书根)   +4 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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