Results 281 to 290 of about 2,036,755 (365)

Towards Robot-Assisted MRI-Guided Lumbar Injections. [PDF]

Int Symp Med Robot
Lehrfeld T, Wang Q, Jain A, Chari V, Iordachita I.   +4 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Design And Fabrication of Motor-Operated Forklift Using Rack and Pinion Mechanism

Sachin S. Patil
openalex   +1 more source

Stapled BH3 Peptides against MCL-1: Mechanism and Design Using Atomistic Simulations

, 2012
Thomas L. Joseph, David P. Lane, Chandra S. Verma   +2 more
openalex   +2 more sources

Compliant Glass Mechanism Instrumented with a Bragg Grating to Measure Indentation Force. [PDF]

Micromachines (Basel)
Marchandise M, Chafai A, Caucheteur C, Lambert P.   +3 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A comprehensive review of mitochondrial fluorescent probes: Design principles, fluorophore engineering, and functional parameter sensing. [PDF]

Mater Today Bio
Peng F, Wang B, Chai R, Xue M, Wu A, Lv Y, Tian H, Yu J, Pang G, Hao B, Gao B.   +10 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

A Bio-Inspired Ring-Cutting and Compliant Clamping Mechanism for Selective Harvesting of Flexible-Stem Crops in Complex Terrain. [PDF]

Biomimetics (Basel)
Du J, Chen C, Zhang Y, Zhang F, Zhang X, Wang H.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source