Results 121 to 130 of about 1,876,013 (306)

AN AGENDA FOR THE DESIGN AND STUDY OF INTERNATIONAL ENVIRONMENTAL AGREEMENTS [PDF]

open access: yes
The combination of a general greening of international political debate, and the events of 1992 at the Rio Earth summit have led to great interest in the question of global environmental protection. While it is recognized that international environmental
Batabyal, Amitrajeet A.
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Why Every Economist Should Learn Some Auction Theory [PDF]

open access: yes
This is an Invited paper for the World Congress of the Econometric Society held in Seattle in August 2000. We discuss the strong connections between auction theory and "standard" economic theory, and argue that auction-theoretic tools and intuitions can ...
Paul Klemperer
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Effect of Process Parameters on the Mechanical Properties of Simultaneous Double-Sided Friction Stir Welding Joints

open access: yesChinese Journal of Mechanical Engineering
Currently, conventional single-sided friction stir welding is primarily suitable for joining thin plate aluminum alloys, and its application to thick plates is still challenging in terms of welding efficiency and joint mechanical properties. Simultaneous
Shaofei Meng   +5 more
doaj   +1 more source

Modeling and Optimization of Structural Parameters for High-Efficiency Multi-Jet Polishing of Optical Glass

open access: yesMicromachines
Multi-jet polishing (MJP) is a promising method for enhanced polishing efficiency by integrating multiple nozzles, allowing for the high-efficiency polishing of large-scale surfaces.
Zhongchen Cao   +3 more
doaj   +1 more source

Mechanism Design Theory: How to Implement Social Goals [PDF]

open access: yes, 2008
The theory of mechanism design can be thought of as the engineering side of economic theory. One begins by identifying a social or economic goal. The theory then addresses the question of whether or not an appropriate institution or procedure (that is, a mechanism) could be designed to attain that goal.
openaire   +1 more source

Computational Mechanism Design: A Call to Arms

open access: yes, 2003
Game theory has developed powerful tools for analyzing decision making in systems with multiple autonomous actors. These tools, when tailored to computational settings, provide a foundation for building multiagent software systems.
Dash, Rajdeep K   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Agri-environmental Regulation on the Back of a Data Envelopment Analysis [PDF]

open access: yes
A land retirement policy whereby land is taken out of agriculture and converted to natural vegetation or forestry has the potential to reduce environmental damage related to dryland salinity in Western Australia.
Chambers, Robert G.   +2 more
core   +1 more source

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