Results 1 to 10 of about 223 (85)
RNA-binding proteins orchestrating immunity in plants. [PDF]
SUMMARY RNA‐binding proteins (RBPs) direct the function and fate of RNA throughout the RNA lifecycle and play important roles in plant immunity, orchestrating the post‐transcriptional reprogramming of the transcriptome following induction of plant immune responses, a process that we term ‘RBP‐mediated immunity’. Although the importance of specific RBPs
Bach-Pages M +4 more
europepmc +2 more sources
Engineering microalgae for water phosphorus recovery to close the phosphorus cycle. [PDF]
Summary As a finite and non‐renewable resource, phosphorus (P) is essential to all life and crucial for crop growth and food production. The boosted agricultural use and associated loss of P to the aquatic environment are increasing environmental pollution, harming ecosystems, and threatening future global food security.
Wang L +10 more
europepmc +2 more sources
Platelet response to influenza vaccination reflects effects of aging. [PDF]
Platelets mediate innate immune responses as well as thrombosis. We found an age‐associated increase in platelet activation RNAs, further increased in skilled nursing facility (enriched for frailty) vs. community‐dwelling (largely non‐frail) older adults. Tensor decomposition analysis revealed distinct trajectories of platelet activation following high‐
Konstorum A +15 more
europepmc +2 more sources
Emerging Roles of Macrophage Polarization in Osteoarthritis: Mechanisms and Therapeutic Strategies. [PDF]
Macrophages are key players in osteoarthritis (OA) pathology. In this review, we focus on synovial macrophages, adipose tissue macrophages, and osteoclasts, to investigate their roles in the development of OA. We review recent key findings related to macrophage polarization and OA, including pathogenesis, molecular pathways, and novel therapeutics ...
Yuan Z +6 more
europepmc +2 more sources
Summary Land carbon dynamics in temperate and boreal ecosystems are sensitive to environmental change. Accurately simulating gross primary productivity (GPP) and its seasonality is key for reliable carbon cycle projections. However, significant biases have been found in early spring GPP simulations of northern forests, where observations often suggest ...
Yunpeng Luo +4 more
wiley +1 more source
Pyroptosis in platelets: Thrombocytopenia and inflammation
This review describes the complex mechanisms of pyroptosis in platelets and their relative diseases. Platelet NLRP3 activation is induced via LPS, HMGB1 and S100A8/A9 receptor TLR4, collagen receptor GPVI, and thrombin. Upon NLRP3 activation, NLRP3 forms inflammasome complexes with the ASC and pro‐caspase‐1 that regulate the production of ...
Yang Su, Tiannan Zhang, Rui Qiao
wiley +1 more source
SYNTHESIS AND ANALYSIS OF A MECHANISM GENERATING THE RATIONAL CIRCULAR CUBIC
Based on the mathematical curve named rational circular cubic [2] and on its animation, it was conceived an original mechanism generating this curve.
Mirela CHERCIU, Iulian POPESCU
doaj +4 more sources
ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris +2 more
wiley +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
This work investigates suitable MAC protocols for medical optical wireless body‐area networks (WBANs), focussing on multiple access management. Using realistic channel models, we evaluate the network performance in terms of energy efficiency, quality‐of‐service and scalability for different IEEE protocols, for both intra‐ and extra‐WBAN connectivity in
Christos Giachoudis +5 more
wiley +1 more source

