Results 131 to 140 of about 1,944 (169)

The molecular basis of interaction domains of full-length PrP with lipid membranes.

Nanoscale, 2019
PrP-lipid membrane interactions are critical to PrP structural conversion and neurotoxicity, but its molecular mechanism remains unclear. A two-dimensional histogram of force-distance curves and a worm-like chain model revealed three binding regions at ...
Yangang Pan, Yangang Pan, Bin Wang, Bin Wang, R. Reese, Bingqian Xu   +5 more
semanticscholar   +1 more source

Convergent Regenerative Strategies in PM&R for Musculoskeletal and Hair Restoration: Integration of PRP, Exosomes, and Physical Modalities

Archives of Internal Medicine Research
Regenerative medicine has emerged as a transformative approach for both musculoskeletal disorders and hair follicle dysfunction by targeting shared biological mechanisms underlying tissue repair and renewal.
A. Aabedi, Devendra K. Agrawal
semanticscholar   +1 more source

Comparative analysis of PRR receptors and R genes reveals structural and functional divergence between wild, ancestral, and commercial citrus species

BMC Genomics
Citriculture holds significant socioeconomic importance but is adversely affected by diseases that reduce productivity. Plant disease resistance is typically relies on efficient defense mechanisms - PTI and ETI - involving PRR receptors and R genes ...
Fredson Dos Santos Menezes, R. J. S. Silva, P. Ollitrault, Fabienne Micheli   +3 more
semanticscholar   +1 more source

Calcium Signalling: A Key Mediator in Plant Immune Mechanism

Journal of Advances in Biology & Biotechnology
Plants lack the adaptive immune system found in vertebrates and rely solely on innate defenses composed of two interrelated layers: pattern-triggered immunity (PTI) and effector-triggered immunity (ETI).
Mannadiar Abhinav Vijayan, R. P
semanticscholar   +1 more source

Specialized pro-resolving mediators alleviate inflammation and cartilage breakdown in vitro and may play a pivotal role in platelet-rich plasma

Scientific Reports
Platelet-rich plasma (PRP) is widely used for osteoarthritis, though its mechanism of action remains unclear. Platelet-derived lipoxygenases generate specialized pro-resolving mediators (SPMs), lipids that aid inflammation resolution, potentially ...
C. Leite, A. Bumberger, Gergo Merkely, Katherine Maietta, Emily K Wright, Joanne Borg-Stein, Julia F. Charles, Cale Jacobs, Christian Lattermann   +8 more
semanticscholar   +1 more source

Treatment of distal hypospadias using autologous platelet-rich plasma

Urology Herald
Hypospadias is the most prevalent congenital malformation of the male urogenital tract and the most common penile anomaly. This literature review delineates the most frequently performed hypospadias repair techniques and highlights the evolving paradigms
N. R. Akramov, B. M. Shaikhraziev, R. Batrutdinov, I. N. Khusnullin   +3 more
semanticscholar   +1 more source

Unveiling the molecular mechanisms of human platelet lysate in enhancing endometrial receptivity.

Human Reproduction
STUDY QUESTION Which biological pathways are modulated by primary human endometrial cells in response to in vitro treatment with non-autologous human platelet lysate (HPL)?
Tina Tu-Thu Ngoc Nguyen, Yat Sze Sheila Kwok H, Carol Zhang, S. Russell, Clifford L Librach   +4 more
semanticscholar   +1 more source

Small Extracellular Vesicles From Platelet-Rich and Platelet-Poor Plasma Are Primarily From Platelets and Protect Synoviocytes From IL-1β–Induced Inflammation

American Journal of Sports Medicine
Background: Small extracellular vesicles (sEVs) circulate throughout the body via blood. They contain various cargoes, including microRNA (miRNA), and have known roles in modulating inflammation and disease.
Logan M. Piening, Preston N Wolfe, D. Shepard, L. Fortier, Michael R. Baria   +4 more
semanticscholar   +1 more source

Platelet-Rich Plasma as a Pharmacopuncture Agent in Cervical Myofascial Pain

Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute
Chronic cervical myofascial pain (CMP) is a prevalent musculoskeletal disorder characterized by persistent neck pain, inflammation, functional impairment, and altered pain processing.
Irma Nareswari, A. F. Kamal, Hasan Mihardja, R. E. Yunus, A. Jusuf, A. Harahap, L. K. Wahyuni, R. A. Werdhani, Selfi Handayani, Dion Rukmindar   +9 more
semanticscholar   +1 more source

Responders to Cervical Facet Platelet-Rich Plasma Demonstrate Synergistic Improvements in Pain and Isometric Strength in Chronic Whiplash-Associated Disorders: A Series of Mediation Analyses

Clinics and Practice
Background/Objectives: Platelet-rich plasma (PRP) is emerging as a safe and effective treatment for facet-mediated pain. Studies have demonstrated reductions in pain and improvements in function, both in the short (3 months) and longer term (6 and 12 ...
Ashley D Smith, Benjamin Andruski, G. Deng, Colin Bouma, Marc Pesant, Fiona Magill, R. Burnham   +6 more
semanticscholar   +1 more source