Results 31 to 40 of about 1,944 (169)
Journal of Medicinal Chemistry, 2021 Modern adjuvants for vaccine formulations are immunostimulating agents whose action is based on the activation of pattern recognition receptors (PRRs) by well-defined ligands to boost innate and adaptive immune responses. Monophosphoryl lipid A (MPLA), a
F. A. Facchini +14 more
semanticscholar +1 more source
PlasmatologyPlatelet-rich plasma (PRP) is an autologous blood-derived product utilized nowadays as a treatment for various non-hemostatic, orthopedic, and muscular injuries.
M. R. Pineda-Cortel +7 more
semanticscholar +1 more source
Post-translational modifications in PrP expand the conformational diversity of prions in vivo
Scientific Reports, 2017 Misfolded prion protein aggregates (PrPSc) show remarkable structural diversity and are associated with highly variable disease phenotypes. Similarly, other proteins, including amyloid-β, tau, α-synuclein, and serum amyloid A, misfold into distinct ...
P. Aguilar-Calvo +9 more
semanticscholar +1 more source
Protein Science, 2019 Aggregation of the disordered protein α‐synuclein into amyloid fibrils is a central feature of synucleinopathies, neurodegenerative disorders that include Parkinson's disease.
Chunhua Dong +4 more
semanticscholar +1 more source
Macrophage Polarization in the Osteoarthritis Pathogenesis and Treatment
Orthopaedic Surgery, Volume 17, Issue 1, Page 22-35, January 2025.M1 macrophage polarization is responsible for the etiology and progression of OA. ABSTRACT Osteoarthritis (OA) is a prevalent degenerative disorder that severely impacts quality of life due to pain and disability. Although the pathophysiology of OA remains incompletely understood, recent research highlights the role of synovial inflammation in OA onset
Xiongfei Zou, Hongjun Xu, Wenwei Qian
wiley +1 more source
Journal of Biological Chemistry, 2005 Inherited prion diseases are linked to mutations in the prion protein (PrP) gene, which favor conversion of PrP into a conformationally altered, pathogenic isoform.
L. Fioriti +6 more
semanticscholar +1 more source
Glycomolecules: from “sweet immunity” to “sweet biostimulation”?
Physiologia Plantarum, Volume 176, Issue 6, November/December 2024.Abstract Climate changes and environmental contaminants are daunting challenges that require an urgent change from current agricultural practices to sustainable agriculture. Biostimulants are natural solutions that adhere to the principles of organic farming and are believed to have low impacts on the environment and human health.
I. Boulogne +6 more
wiley +1 more source
Biochemical and nanotechnological approaches to combat phytoparasitic nematodes
Plant Biotechnology Journal, Volume 22, Issue 9, Page 2444-2460, September 2024.Summary The foundation of most food production systems underpinning global food security is the careful management of soil resources. Embedded in the concept of soil health is the impact of diverse soil‐borne pests and pathogens, and phytoparasitic nematodes represent a particular challenge.
Patrick Opdensteinen +4 more
wiley +1 more source
Journal of Medical Science And clinical Research, 2019 Objective: To evaluate use of autologous platelet-rich plasma (PRP) eye drops for the treatment of severe dry eye disease. Materials & Method: This is a retrospective study conducted at a tertiary eye care centre. 30 patients with severe dry eye disease (
R. Gupta +1 more
semanticscholar +1 more source
Diffusion in Networks and the Unexpected Virtue of Burstiness
, 2017 Whether an idea, information, infection, or innovation diffuses throughout a society depends not only on the structure of the network of interactions, but also on the timing of those interactions.
Akbarpour, Mohammad, Jackson, Matthew O.
core +1 more source