Effects of vincristine on the properties of low threshold mechanoreceptors and high threshold mechanoreceptors in the hindpaw glabrous skin of mice [PDF]
Molecular BrainVincristine is an important chemotherapy drug to treat various types of cancer, but it induces peripheral neuropathy, leading to numbness and mechanical allodynia in the hands and feet of patients. The peripheral neuropathy is a dose-limiting toxicity of
Jianguo Gu
exaly +3 more sources
Anterior and Posterior Cruciate Ligaments Mechanoreceptors: A Review of Basic Science
Diagnostics, 2022 Proprioception is a specialized sensory modality encompassing the movement of the joint and its position in space, and it involves the conversion of mechanical deformation of tissues into neural signals.
Aristeidis Zibis +2 more
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A Pollen‐Enhanced Bionic Mechanoreceptor Induced by Asymmetric Ionic Convection in Hydrogel for Sensory‐Augmented Prostheses [PDF]
Advanced ScienceThe growing prevalence of age‐related limb loss underscores the need for prosthetic technologies that restore not only motor function but also authentic sensory feedback.
Zi Hao Guo +7 more
doaj +3 more sources
Medicina, 2023 Background: We investigated whether the distribution of mechanoreceptors in three sections of the anterior talofibular ligament (ATFL) differed. Methods: The ATFL was obtained from 29 ankles of 21 fresh-frozen cadavers and divided into fibular attachment,
Youngkoo Lee +10 more
doaj +2 more sources
npj Flexible Electronics, 2022 Human skin contains slowly adaptive (SA) and rapidly adaptive (RA) mechanoreceptors, which respond differently to external stimuli. Based on human tactile perception principles, the fabrication of a self-powered electronic skin (e-skin) that ...
Aadil Waseem +5 more
doaj +2 more sources
Mechanoreceptors of the Posterior Cruciate Ligament [PDF]
Journal of International Medical Research, 2008 The mechanical role of the anterior and posterior cruciate ligaments in the passive and functional stability of the knee joint has been well documented. Both these knee joint ligaments contain Ruffini, Pacinian, Golgi and free nerve endings with different capabilities of providing the central nervous system with information regarding movement and ...
George Tzanakakis
exaly +4 more sources
What Is Inside the Sinus Tarsi? Mechanoreceptor Distribution, Typing and Clinical Relevance—A Histological and Immunohistochemical Synthesis [PDF]
BiomedicinesThe sinus tarsi, a small osseoligamentous recess of the subtalar joint, contains multiple soft-tissue structures with a complex sensory network. However, the detailed neural architecture and clinical significance of its innervation remain incompletely ...
Alberto Arceri +9 more
doaj +2 more sources
Synthetic mechanoreceptor engineering: From genetic encoding to DNA nanotechnology-based reprogramming [PDF]
Mechanobiology in MedicinePrecise modulation of mechanoreceptor-mediated signal transduction is crucial for decoding cellular mechanotransduction mechanisms and programming cell fate.
Sihui Yang, Zhou Nie
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Analysis of Nerve Endings in the Superior Labrum-Biceps Complex by Fluorescence Immunohistochemistry and Confocal Laser Microscopy [PDF]
Revista Brasileira de Ortopedia, 2022 Objectives The capsuloligamentous structures of the shoulder work as static stabilizers, together with the biceps and rotator cuff muscles, increasing the contact surface of the glenoid cavity. Free nerve endings and mechanoreceptors have been identified
Maria L. C. Cavalcante +5 more
doaj +1 more source
Molecular Brain, 2023 Nav1.8-positive afferent fibers are mostly nociceptors playing a role in mediating thermal and mechanical pain, but mechanoreceptors within these afferents have not been fully investigated. In this study, we generated mice expressing channel rhodopsin 2 (
Akihiro Yamada +5 more
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