Results 161 to 170 of about 643,520 (291)

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Correction: Licochalcone D reduces H₂O₂-induced SH-SY5Y cell neurotoxicity by regulating reactive oxygen species. [PDF]

Front Pharmacol
Kwak AW, Park S, Oh HN, Shim JH, Yoon G, Kim WK.   +5 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Geopolitical tension as an emerging structural determinant of population mental health. [PDF]

J R Soc Med
Torales J, Castaldelli-Maia JM, Ventriglio A.   +2 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Functional implications of polygenic risk for schizophrenia in human neurons. [PDF]

Nat Commun
Michael Deans PJ, Retallick-Townsley KG, Li A, Seah C, Johnson J, Garcia Gonzalez J, Cao E, Schrode N, Yu A, Cartwright S, Voloudakis G, Zhang W, Wang M, Fullard JF, Girdhar K, Stahl E, Akbarian S, Zhang B, Roussos P, O'Reilly P, Huckins LM, Brennand KJ.   +21 more
europepmc   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Correction: RBM39 shapes innate immunity by controlling expression of key factors of the interferon response. [PDF]

Front Immunol
Li TF, Rothhaar P, Lang A, Grünvogel O, Colasanti O, Ugarte SMO, Traut J, Piras A, Acosta-Rivero N, Gonçalves Magalhães V, Springer E, Betz A, Huang HE, Park J, Qiu R, Gnouamozi GE, Mehnert AK, Dao Thi VL, Urban S, Muckenthaler M, Schlesner M, Wohlleber D, Binder M, Bartenschlager R, Pichlmair A, Lohmann V.   +25 more
europepmc   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

An integrated method for lightweight design and additive manufacturing of UAV arms. [PDF]

PLoS One
Wang R, Yang W, Pang G, Liu Z, Rao X, Yu Y.   +5 more
europepmc   +1 more source