Results 41 to 50 of about 107,277 (310)

Media reform: in shallows and miseries [PDF]

open access: yes, 2013
This paper recounts the story of the 2013 media reforms - their introduction, the hurried investigations which attempted to explore their intentions and possible outcomes, and their eventual demise. Introduction As a result of an investigation into the
Rhonda Jolly
core  

Multi-HM: A Chinese Multimodal Dataset and Fusion Framework for Emotion Recognition in Human–Machine Dialogue Systems

open access: yesApplied Sciences
Sentiment analysis is pivotal in advancing human–computer interaction (HCI) systems as it enables emotionally intelligent responses. While existing models show potential for HCI applications, current conversational datasets exhibit critical limitations ...
Yao Fu   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Media reviews: all sound and fury? [PDF]

open access: yes, 2012
This report provides background on recent media reviews in Australia, and assesses what they may mean for the future. Since the seventeenth century the media have been seen as the watchdogs of democracy— guardians of the public interest, protecting the ...
Rhonda Jolly
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Data Element Sharing in Convergence Media Ecology Based on Evolutionary Game

open access: yesApplied Sciences, 2023
As a new factor of production, data element has profoundly changed our mode of production, lifestyle and social governance style. The sharing of a data element in the convergence media ecology can greatly improve the circulation of a data element and ...
Hongbin Hu   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Horror 2.0 (On Demand): The Digital Convergence of Horror Film Culture

open access: yes, 2014
This article examines the horror movie industry’s mobilization of web content and digital distribution outlets, such as video-on-demand (VOD), and how specific fan practices get encoded into business models shaping web 2.0 strategies.
Tompkins, Joe
core   +1 more source

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