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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
DBDST-Net: Dual-Branch Decoupled Image Style Transfer Network
InformationThe image style transfer task aims to apply the style characteristics of a reference image to a content image, generating a new stylized result. While many existing methods focus on designing feature transfer modules and have achieved promising results ...
Na Su +4 more
doaj +1 more source
Editorial: BILETA special issue: Technology and Legal Education [PDF]
, 2014 Fragmentation and convergence are two discoursal lenses that have been used to view changes that have taken place in the domains of legal services,the legal profession, regulation and legal education. While they may appear orthogon al, the relationships
Maharg, P
core +3 more sources
Extending Modular Semantics for Bipolar Weighted Argumentation (Technical Report)
, 2019 Weighted bipolar argumentation frameworks offer a tool for decision support and social media analysis. Arguments are evaluated by an iterative procedure that takes initial weights and attack and support relations into account. Until recently, convergence
Potyka, Nico
core +1 more source
STRATEGI KONVERGENSI MEDIA PADA SURAT KABAR DAERAH (STUDI KASUS PADA MEDIA TRIBUN KALTIM) [PDF]
, 2023 Media began to monitor technological developments related to the shift of media consumption habits to digital media as an impact of the development of information and communication technology.
Yuliansyah, Muhammad Rafli
core
Media Convergence Policy Issues [PDF]
, 2016 Digital technologies are frequently said to have converged. This claim may be made with respect to the technologies themselves or to restructuring of the media industry over time. Innovations that are associated with digitalization (representing analogue signals by binary digits) often emerge in ways that cross the boundaries of earlier industries ...
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Journalism and Media Convergence [PDF]
, 2013 Journalism is under ever-increasing pressure, due in large part to the phenomenon of media convergence. Not only does media convergence redefine the tasks of journalists and newsrooms, it also re-shapes the business environments of media companies. In this book, international media practitioners and researchers describe and analyze the relationships ...
Stephan Russ-Mohl +2 more
openaire +2 more sources
Applied SciencesSentiment analysis is pivotal in advancing human–computer interaction (HCI) systems as it enables emotionally intelligent responses. While existing models show potential for HCI applications, current conversational datasets exhibit critical limitations ...
Yao Fu +4 more
doaj +1 more source
Editors’ Introduction: Approaching the online audience: new practices, new thinking [PDF]
, 2011 Convergence culture, participatory culture, user generated content, interactive media; these are all now familiar terms within contemporary media and communication studies that have risen to distinguish emergent content across digital platforms and ...
Athique, Adrian M. +3 more
core +1 more source