Results 71 to 80 of about 643,520 (291)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

ProTriPlay: A trinity framework for professional interactive theater based on LLM

Complex & Intelligent Systems
Interactive theater powered by large language models faces significant challenges, including limited player agency in plot development, restricted interaction variety, and a lack of personalized experiences.
Yinglong Yu, Hao Shen, Ming Yang, Yu Wang, Yanyu Liu   +4 more
doaj   +1 more source

A Music-Driven Dance Generation Method Based on a Spatial-Temporal Refinement Model to Optimize Abnormal Frames

Sensors
Since existing music-driven dance generation methods have abnormal motion when generating dance sequences which leads to unnatural overall dance movements, a music-driven dance generation method based on a spatial-temporal refinement model is proposed to
Huaxin Wang, Yang Song, Wei Jiang, Tianhao Wang   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A Blockchain Copyright Protection Scheme Based on CP-ABE Scheme with Policy Update

Sensors
Although the copyright protection schemes supported by blockchain have significantly changed traditional copyright data management, there are still some data security challenges that cannot be ignored, especially the secure access and controllable ...
Jian Jiang, Yulong Gao, Yufei Gong, Zhengtao Jiang   +3 more
doaj   +1 more source

Media Convergence Meets Deconvergence [PDF]

, 2017
Abstract This introductory chapter explains that there is a widely shared understanding of the imperative nature of media convergence, which is based on different notions connecting positive goals such as efficiency, synergy, simplification, information abundance, participation, availability and multimodality.
Peil, Corinna, Sparviero, Sergio
openaire   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

A Study of Risk Communication and Perceptions of Official and Public Agendas in the Context of Emergencies: Based on the Itaewon Stampede

SAGE Open
On October 29, 2022, a large-scale stampede occurred in Seoul, South Korea, which caused worldwide shock and garnered global attention and discussion. In this article, a study on the thematic characteristics of social media platforms during major sudden ...
Yanchun Chen, Gaogao Peng, Yuwei Tu, Tianzhi Ren   +3 more
doaj   +1 more source

Mass Media and Polarisation Processes in the Bounded Confidence Model of Opinion Dynamics [PDF]

This paper presents a social simulation in which we add an additional layer of mass media communication to the social network \'bounded confidence\' model of Deffuant et al (2000).
Gary Mckeown, Noel Sheehy
core