Results 51 to 60 of about 251,649 (296)

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

open access: yesAdvanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge   +14 more
wiley   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

open access: yesAdvanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi   +3 more
wiley   +1 more source

Weekdays and holidays of office plankton, or the cult of Friday as a fact of modern (media) culture / Будни и праздники офисного планктона, или культ пятницы как факт современной (медиа)культуры

open access: yesИндустрии впечатлений: Технологии социокультурных исследований
The article offers an interpretation of the new cultural practice of celebrating the end of the working week with mass real and media actions. Their mass character allows us to talk about the formation of the cult of Friday.
Tatyana Shmeleva / Шмелева Татьяна Викторовна
doaj   +1 more source

Ritual and cult crimes and the characteristics of their perpetrators [PDF]

open access: yesNBP: Nauka, bezbednost, policija, 2015
In this paper the criminality aspect of ritual crimes that are the result of accepting the cult value system is discussed. Successfully finding and prosecuting perpetrators of such acts impose requirements of above-average knowledge of context and value ...
Luković Zoran   +2 more
doaj  

Релігійне телебачення та феномен медіа-релігійності (Religious television and phenomenon of media-religion) [PDF]

open access: yes, 2016
У статті розглядається феномен медіа-релегійності та релігійного телебачення. (The phenomenon of media-religion is associated with mass communication processes.
Петрушкевич, М. (M. Petrushkevych)
core  

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

Det globale prisuddelingsshow

open access: yesAkademisk Kvarter, 2017
In The global awards - cross-mediality, mainstream movie cult and celebrity matrix, Helle Kannik Haastrup argues that awards have to be considered media events with several functions at the same time.
Helle Kannik Haastrup
doaj   +1 more source

Cult Film Dan Analisa Semiotika Film Pada Nagabonar Jadi 2 [PDF]

open access: yes, 2009
Cult films phenomena have attracts lots of discussion among film critics or communication experts especially for those who studied media, nevertheless research on the films using semiotic remains sparsely.
Faizal, A. R. (Akhmad)
core  

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Vendor Types, Attendance, Experience and Sales 2019–2021: Evidence From Five Rural Oregon Farmers Markets

open access: yesAgribusiness, EarlyView.
ABSTRACT Farmers markets provide a direct‐to‐consumer marketing path for farmers and small businesses, facilitating customer discovery and product refinement. This paper explores farmers markets as a business incubator, with a focus on beginning vendors and resilience to a shock, namely, COVID‐19 market restrictions.
Mallory L. Rahe   +2 more
wiley   +1 more source

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