Results 111 to 120 of about 299,155 (301)
Infrastructure, the crisis, and pension funds [PDF]
, 2009 Infrastructure investment has been an important element in the economic stimulus packages introduced to try and deal with the effects of the recession.
Hall, David
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Saving the euro – a multimodal analysis of metaphors depicting the Eurozone crisis1 [PDF]
Ibérica, 2017 Much of the research into the topic of financial crises has centered mainly on verbal metaphors whereas a visual and multimodal aspect of the phenomenon has remained rather underrepresented.
Nadežda Silaški , Tatjana Đurović
doaj
Social Media + Society, 2018 Sentiment analysis is an increasingly popular instrument for the analysis of social media discourse. Sentiment scores seemingly represent an objective means of assessing the mood of social media users, consumers, and the public at large. Similar to other
Cornelius Puschmann, Alison Powell
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Initial Coin Offerings: Innovation, Democratization and the SEC [PDF]
, 2018 Initial coin offerings are a source of controversy in the world of startup fundraising, and their legality is, at best, an open question. Amid soaring valuations and rumors of looming SEC action, investors and issuers alike are scrambling to forge a path
Preston, Jay
core +1 more source
Social Media and Sentimental Analysis: Central Bank of Nigeria Currency Redesign Policy
Abstract The identification and measurement of an online audience through the social media platform capitalise on the tonality of emotions on the social media presence. On October 20, the most populous country and acclaimed Africa’s largest economy, Nigeria announced the plans to redesign 200, 500 and 1000 banknotes in replacement of the ...
Kayode Abiodun Oladapo +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source