Results 81 to 90 of about 299,155 (301)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
SOCIAL MEDIA, RELIGION AND RELIGIOSITY IN PAKISTAN IN THE ERA OF DISRUPTION
Hamdard Islamicus, 2021 We are living in an era of disruption and the technological advancements have enabled us to manage work and family through remote access; replacing paper currency with cryptocurrency & phone wallets; and call centres with robot assistance. Technological
DR. TAHMINA RASHID
doaj +2 more sources
Strategic Media, Cynical Public? Examining the Contingent Effects of Strategic News Frames on Political Cynicism in the UK [PDF]
, 2010 Through the use of experimental methods, this study examines the claim that strategic news engenders political cynicism. Firstly, it builds upon previous theory by conceptualising and measuring political cynicism at both issue-specific and global levels.
Jackson, Dan
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Toward a More Substantive Media Ecology: Postman’s Metaphor Versus Posthuman Futures
International Journal of Communication, 2014 The metaphor of “ecology,” common in vernacular and academic discourse about communication media, can inhibit substantively ecological thinking about communication.
Niall P. Stephens
doaj
A Historical Approach to Webcomics: Digital Authorship in the Early 2000s
The Comics Grid: Journal of Comics Scholarship, 2019 Available on the web and often excerpted by the visually-oriented algorithms of social media feeds, webcomics arguably have the broadest reach of any form of comics, yet they remain under-theorized. Given the close association with the development of the
Leah Misemer
doaj +2 more sources
Argentina’s “Netflix tax” isn’t surprising [PDF]
, 2014 LSE MSc student Ayden Fabien Férdeline looks at Argentina’s new levy on payments to foreign providers of streaming services and argues that the South American country is not trying to curtail media dissent, but is trying to keep foreign currency from ...
Ferdeline, Ayden Fabien
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The news that doesn't make the news sources for alternative current affairs reporting
Information for Social Change, 1995 The distorting influence of all mass media has been demonstrated for many years in the work of such as Noam Chomsky, John Pilger and the Glasgow University Media Group.
Chris Atton
doaj +1 more source