Results 121 to 130 of about 21,192 (293)
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Dependency theory : Melvin L. Defleur dan Sandra Ball Rokeach
John Naisbitt and Patricia Aburdence say in their book Megatrend 2000 (1991) that there is a Global Village. It means that people might know what happened in a country even society.
Rafiq, Mohd.
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The Social Construction of the Arab Online Media Audience: Paradoxical Issues in the Digital Era
The online media services are substantially changing the landscape of audience consumption. Indeed, there is a need to know why some of the Arab audience members use online media, and how they interact with it.
Wail Ismail A. Barry
doaj
Is Political Information Over Facebook Credible? A Look at the 2020 Presidential Election
Much controversy still exists surrounding the events before, during, and after the 2020 U.S. presidential election. Some of this is attributable to voters’ uncertainty, driven by conflicting messages transmitted over social media, about the credibility ...
Kristina Harrison +3 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
While enterprise social media (ESM) increasingly plays a vital role in improving teamwork in organizations, our understanding of how ESM is used by team members is still limited.
Chen, Xiayu +2 more
core
Television and Dependency: A Case Study of Policy Making in Fiji and Papua New Guinea [PDF]
Dependency theory continues to offer the development researcher attractive possibilities for heuristic claims about relationships of cultural or economic dependency between nations.
Horsfield, Bruce +2 more
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source

